Oxidative stress, mitochondrial dysfunction, and aging

H Cui, Y Kong, H Zhang - Journal of signal transduction, 2012 - Wiley Online Library
Oxidative damage affects replication and transcription of mtDNA and results in a decline in
mitochondrial function … involved in oxidative stress response and mitochondrial function has …

The role of oxidative stress, mitochondrial function, and autophagy in diabetic polyneuropathy

S Sifuentes-Franco, FP Pacheco-Moisés… - Journal of diabetes …, 2017 - Wiley Online Library
… and mitochondrial … -oxidative stress (NOS) and endoplasmic reticulum stress. Hyperglycemia
provokes the appearance of micro- and macrovascular complications and favors oxidative

Mitochondrial function is differentially affected upon oxidative stress

SM Cardoso, C Pereira, CR Oliveira - Free Radical Biology and Medicine, 1999 - Elsevier
… In the present study we analyzed the effect of oxidative stress, induced by ascorbate/iron,
on the activity of the mitochondrial respiratory chain complexes in rat brain cortex …

Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress

AP Rolo, CM Palmeira - Toxicology and applied pharmacology, 2006 - Elsevier
… This review focuses on a range of mitochondrial factors important in the pathogenesis of …
on mitochondrial function and suggest the possibility of regulation of mitochondrial function at a …

Oxidative stress, apoptosis, and mitochondrial function in diabetic nephropathy

S Sifuentes-Franco, DE Padilla-Tejeda… - International journal …, 2018 - Wiley Online Library
… The increase in the production of oxidative stress (OS) is induced by the persistent
hyperglycemic state capable of producing oxidative damage to the macromolecules (lipids, …

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

AH Bhat, KB Dar, S Anees, MA Zargar… - Biomedicine & …, 2015 - Elsevier
… type protein it reduces mitochondrial function, increases oxidative stress. Its overexpression
… about the different mitochondrial targets in toxic oxidative stress. Oxidative stress is an …

[HTML][HTML] Oxidative stress, mitochondrial damage and neurodegenerative diseases

C Guo, L Sun, X Chen, D Zhang - Neural regeneration research, 2013 - journals.lww.com
… of oxidative stress and mitochondrial damage to the onset of neurodegenerative eases and
discusses strategies to modify mitochondrial … can impair mitochondrial function and enhance …

Oxidative stress and mitochondrial function with aging–the effects of calorie restriction

BJ Merry - Aging cell, 2004 - Wiley Online Library
… Accumulated oxidative stress resulting from a gradual shift in the redox status of tissues is …
oxidative stress. This conclusion is based on the increase in tissues with age of the oxidation

Oxidative stress, mitochondrial function, and acute glutamate excitotoxicity in cultured cerebellar granule cells

RF Castilho, MW Ward… - Journal of …, 1999 - Wiley Online Library
On exposure to glutamate, cultured rat cerebellar granule cells undergo a delayed Ca 2+
deregulation (DCD), which precedes and predicts cell death. We have previously shown that …

Diabetes, oxidative stress, nitric oxide and mitochondria function

M Friederich, P Hansell, F Palm - Current diabetes reviews, 2009 - ingentaconnect.com
… basic functions of the mitochondria and focuses on the complex interplay between oxidative
stress, nitric oxide and uncoupling proteins in regulating mitochondria function with special …