Neurodegeneration by oxidative stress: a review on prospective use of small molecules for neuroprotection
E Singh, G Devasahayam - Molecular Biology Reports, 2020 - Springer
… to oxidative damages to neuronal cells. In many of such cases, use of antioxidants decreases
oxidative stress … This review intends to compile approach of managing oxidative stress in …
oxidative stress … This review intends to compile approach of managing oxidative stress in …
Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols
LM Hyman, KJ Franz - Coordination chemistry reviews, 2012 - Elsevier
… This review article provides an overview of small molecule fluorescent sensors designed to
detect factors associated with oxidative stress and neurodegenerative disease, in particular …
detect factors associated with oxidative stress and neurodegenerative disease, in particular …
Therapeutic potential of small molecules targeting oxidative stress in the treatment of chronic obstructive pulmonary disease (COPD): a comprehensive review
HG Dailah - Molecules, 2022 - mdpi.com
… Oxidative stress (OS) takes place when various reactive species and free radicals swamp …
Therefore, targeting systemic and local OS with therapeutic agents such as small molecules …
Therefore, targeting systemic and local OS with therapeutic agents such as small molecules …
Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress
AT Shaw, MM Winslow… - Proceedings of the …, 2011 - National Acad Sciences
… Here we report the results of a small molecule, synthetic lethal … -ras mutant cells, leading to
oxidative stress and cell death. In mice… of lanperisone and reveal oxidative stress pathways as …
oxidative stress and cell death. In mice… of lanperisone and reveal oxidative stress pathways as …
[HTML][HTML] Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation
CA Labarrere, GS Kassab - Frontiers in Nutrition, 2022 - frontiersin.org
… oxidative stress fundamental to control life processes, and (b) limiting excessive oxidative
stress … and stroke), (2) importance of oxidative stress and antioxidants in SARS-CoV-2 infection …
stress … and stroke), (2) importance of oxidative stress and antioxidants in SARS-CoV-2 infection …
Methods for the Discovery and Identification of Small Molecules Targeting Oxidative Stress-Related Protein–Protein Interactions: An Update
X Wu, Q Zhang, Y Guo, H Zhang, X Guo, Q You… - Antioxidants, 2022 - mdpi.com
… identification of small molecules that target oxidative stress-… in the discovery of small molecules
for different types of PPIs. … PPI inhibitors associated with oxidative stress to illustrate the …
for different types of PPIs. … PPI inhibitors associated with oxidative stress to illustrate the …
Small molecules preventing GAPDH aggregation are therapeutically applicable in cell and rat models of oxidative stress
VF Lazarev, AD Nikotina, PI Semenyuk… - Free Radical Biology …, 2016 - Elsevier
… The aim of this study was to search for the small molecules that are able to prevent the
enzyme aggregation and thereby reduce the deleterious effect of oxidative stress in cell and …
enzyme aggregation and thereby reduce the deleterious effect of oxidative stress in cell and …
[HTML][HTML] Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells
… Phenotype-based screening can identify small molecules that … (LUAD) cells, induces oxidative
stress. To identify the target … TPP to uncover targets of small molecules identified by high-…
stress. To identify the target … TPP to uncover targets of small molecules identified by high-…
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
HJ Forman, H Zhang - Nature Reviews Drug Discovery, 2021 - nature.com
… oxidative stress concerns the scavenging of superoxide (O 2 •− ) or H 2 O 2 by small molecules…
more rapidly with those oxidants than small molecules do and provide the predominant …
more rapidly with those oxidants than small molecules do and provide the predominant …
Pharmacotherapy against oxidative stress in chronic kidney disease: Promising small molecule natural products targeting nrf2-ho-1 signaling
The global burden of chronic kidney disease (CKD) intertwined with cardiovascular disease
has become a major health problem. Oxidative stress (OS) plays an important role in the …
has become a major health problem. Oxidative stress (OS) plays an important role in the …
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