Tauroursodeoxycholic Acid Alleviates H2O2-Induced Oxidative Stress and Apoptosis via Suppressing Endoplasmic Reticulum Stress in Neonatal Rat …

L Zhang, Y Wang - Dose-Response, 2018 - journals.sagepub.com
… Attenuates H 2 O 2 -Induced Oxidative Stress in NRC … are important indices of oxidative
stress status. To further evaluate the effects of TUDCA on H 2 O 2 -induced oxidative stress, we …

Tauroursodeoxycholic acid protects retinal pigment epithelial cells from oxidative injury and endoplasmic reticulum stress in vitro

RH Alhasani, M Almarhoun, X Zhou, J Reilly… - Biomedicines, 2020 - mdpi.com
… potential of TUDCA against oxidative damage and endoplasmic reticulum (ER) stress in
human RPE cells. We found that TUDCA attenuated H 2 O 2 -evoked oxidative damage and …

Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response

Y Hou, J Luan, T Huang, T Deng, X Li, Z Xiao… - Journal of …, 2021 - Springer
… Thus, we are aiming to investigate the effects of TUDCA on oxidative stress, inflammation, …
that TUDCA could reduce oxidative stress, thus we want to ascertain whether TUDCA could …

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases

K Khalaf, P Tornese, A Cocco, A Albanese - Translational …, 2022 - Springer
… Experimental evidence on the mechanisms underlying TUDCA’… TUDCA exerts its effects
not only by regulating and inhibiting the apoptotic cascade, but also by reducing oxidative stress

Treatment of in vitro-Matured Bovine Oocytes With Tauroursodeoxycholic Acid Modulates the Oxidative Stress Signaling Pathway

EM Pioltine, CB Costa, L Barbosa Latorraca… - Frontiers in Cell and …, 2021 - frontiersin.org
… of tauroursodeoxycholic acid (TUDCA; 50, 200, and 1,000 μM), a chemical chaperone for
relieving ER stress, … medium with 200 μM of TUDCA decreased ROS production and increased …

[HTML][HTML] Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

YP Vandewynckel, D Laukens, L Devisscher… - Oncotarget, 2015 - ncbi.nlm.nih.gov
TUDCA did not affect oxidative stress-induced cytotoxicity in vitro or hepatic oxidative stress
in … the chemopreventive effect of TUDCA was not mediated by directly antagonizing oxidative

Aging and gender-related effects of tauroursodeoxycholic acid treatment on liver functions, plasma lipid profile, and oxidative stress

S Han - Cukurova Medical Journal, 2022 - dergipark.org.tr
oxidative stress markers due to aging and gender, and to investigate how these parameters
change with ER stress inhibitor tauro-ursodeoxycholic acid (TUDCA) … stress inhibitor TUDCA

Administration of tauroursodeoxycholic acid prevents endothelial dysfunction caused by an oral glucose load

LK Walsh, RM Restaino, M Neuringer… - Clinical …, 2016 - portlandpress.com
oxidative stress, we examined plasma levels of TBARS and nitrotyrosine, two common markers
of oxidative stress… placebo condition, nor an effect of TUDCA on these markers. However, …

Tauroursodeoxycholate—bile acid with chaperoning activity: molecular and cellular effects and therapeutic perspectives

M Kusaczuk - Cells, 2019 - mdpi.com
… Apart from that, TUDCA has also been found to reduce oxidative stress, suppress apoptosis,
and … Tauroursodeoxycholic acid (TUDCA) is a taurine conjugate of ursodeoxycholic …

Tauroursodeoxycholic acid ameliorates lipopolysaccharide-induced depression like behavior in mice via the inhibition of neuroinflammation and oxido-nitrosative …

L Cheng, C Huang, Z Chen - Pharmacology, 2019 - karger.com
… neuroinflammation and oxidative stress in depression. Tauroursodeoxycholic acid (TUDCA)…
to prevent neuroinflammation and oxidative stress. In this study, we investigated the effect of …