Nitric oxide and superoxide: interference with hypoxic signaling

B Brüne, J Zhou - Cardiovascular research, 2007 - academic.oup.com
… Low oxygen availability (hypoxia), nitric oxide (NO) or superoxide can inhibit PHD to
accumulate HIF-1α. Stabilized HIF-1α associates with HIF-1β to recognize the hypoxia response …

Sources of vascular nitric oxide and reactive oxygen species and their regulation

J Tejero, S Shiva, MT Gladwin - Physiological reviews, 2019 - journals.physiology.org
… Architecture of nitric oxide synthases (NOS). A: the arrangement of the domains in the NOS
monomer. The oxygenase/heme domain (red) is connected to the reductase domain by a …

Fabrication and in vivo evaluation of nitric oxide-releasing electrochemical oxygen-sensing catheters

MC Frost, ME Meyerhoff - Methods in enzymology, 2004 - Elsevier
… affect the flux of analyte to the sensor (the wall effect). Nitric oxide (NO) has been shown to
have a wide range of physiological roles in vivo. Nitric oxide is released endogenously on a …

Regulation of oxygen distribution in tissues by endothelial nitric oxide

VM Victor, C Nunez, P D'Ocón, CT Taylor… - Circulation …, 2009 - Am Heart Assoc
Nitric oxide (NO) decreases cellular oxygen (O 2 ) … in the microcirculation using the fluorescent
oxygen-probe Ru(phen) 3 2… Nitric oxide (NO) synthase in the vasculature (endothelial NO …

NO and CO as second messengers in oxygen sensing in the carotid body

NR Prabhakar - Respiration physiology, 1999 - Elsevier
… It is being increasingly appreciated that nitric oxide (NO) and carbon monoxide (CO) are …
significance in oxygen chemoreception. The NO synthesizing enzyme, nitric oxide synthase, is …

Improved in Vivo Performance of Amperometric Oxygen (PO2) Sensing Catheters via Electrochemical Nitric Oxide Generation/Release

H Ren, MA Coughlin, TC Major, S Aiello… - Analytical …, 2015 - ACS Publications
… controlled release method for nitric oxide (NO) (based on … oxygen sensor within a dual
lumen catheter configuration for the continuous in vivo sensing of the partial pressure of oxygen (…

Nitric oxide function during oxygen deprivation in physiological and stress processes

I Manrique-Gil, I Sánchez-Vicente… - Journal of …, 2021 - academic.oup.com
… that have evolved to maintain specific requirements for oxygen (O 2 ), leading to a correct …
compounds that includes O 2 , ethylene, and nitric oxide. In view of recent scientific advances, …

Measurement of nitric oxide and reactive oxygen species in the vascular wall

R Rodriguez-Rodriguez… - Current Analytical …, 2012 - ingentaconnect.com
… Abstract: Vascular generation of nitric oxide (NO) plays an important role in the regulation
of blood flow, and is counterbalanced by the formation of radical oxygen species (ROS). Thus, …

How Do Heme-Protein Sensors Exclude Oxygen? Lessons Learned from Cytochrome c′, Nostoc puntiforme Heme Nitric Oxide/Oxygen-Binding Domain, and …

A Tsai, E Martin, V Berka, JS Olson - Antioxidants & redox signaling, 2012 - liebertpub.com
… tengcongensis heme nitric oxide/oxygen-binding domain (Tt H-NOX; top) and Tt sensor of
nitric oxide (SONO; bottom) in the heme binding pocket. Same sensor protein was isolated …

Nitric oxide sensing revisited

A Wong, N Hu, X Tian, Y Yang, C Gehring - Trends in Plant Science, 2021 - cell.com
Nitric oxide (NO) sensing is an ancient trait enabled by hemoproteins harboring a highly
conserved Heme-Nitric oxide/OXygen (H-NOX) domain that operates throughout bacteria, fungi, …