Reactive oxygen species and colorectal cancer

S Sreevalsan, S Safe - Current colorectal cancer reports, 2013 - Springer
Several agents used for treatment of colon and other cancers induce reactive oxygen species
(ROS), and this plays an important role in their anticancer activities. In addition to the well-…

Reactive oxygen species and colorectal cancer

S Lin, Y Li, AA Zamyatnin Jr, J Werner… - Journal of cellular …, 2018 - Wiley Online Library
… Comparing with the normal counterparts, cancer cells generate more reactive oxygen
species (ROS). Therefore, it is possible that a higher level of ROS inducing cancer cell death …

Microenvironmental reactive oxygen species in colorectal cancer: involved processes and therapeutic opportunities

MA Sorolla, I Hidalgo, A Sorolla, R Montal, O Pallisé… - Cancers, 2021 - mdpi.com
Colorectal cancer is a disease associated with a high mortality rate. During the … modify
cancer proliferation and metastasis. These regulatory agents include reactive oxygen species (…

High oxygen radical production in patients with sporadic colorectal cancer

EMJ van der Logt, HMJ Roelofs, T Wobbes… - Free Radical Biology …, 2005 - Elsevier
… of colon cancer development. The present study investigates whether ROS production by
whole blood may contribute to the etiology of colorectal cancer (CRC). Whole–blood oxygen

Role of reactive oxygen species in the abrogation of oxaliplatin activity by cetuximab in colorectal cancer

V Santoro, R Jia, H Thompson, A Nijhuis… - … the National Cancer …, 2016 - academic.oup.com
Background: The antibody cetuximab, targeting epidermal growth factor receptor (EGFR), is
used to treat metastatic colorectal cancer (mCRC). Clinical trials suggest reduced benefit …

Reactive oxygen species in colorectal cancer: The therapeutic impact and its potential roles in tumor progression via perturbation of cellular and physiological …

R Moradi‐Marjaneh, SM Hassanian… - Journal of cellular …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) are produced by mitochondria during metabolism. In
physiological states, the production of ROS and their elimination by antioxidants are kept in …

Anti-colorectal cancer activity of macrostemonoside A mediated by reactive oxygen species

Y Wang, Q Tang, S Jiang, M Li, X Wang - Biochemical and biophysical …, 2013 - Elsevier
… Therefore, significant effort has been exerted to identify novel drug targets to reduce incidence
and malignancy of colorectal cancer cells. Reactive oxygen species (ROS), which are the …

[HTML][HTML] Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species

J Zhou, P Li, X Xue, S He, Y Kuang, H Zhao, S Chen… - Toxicology letters, 2013 - Elsevier
cancer cells. To explore the potential mechanisms that salinomycin could specifically target
on therapy-resistant cancer cells in colorectal cancers, … an original colorectal cancer cell line. …

Proteomics identification of ITGB3 as a key regulator in reactive oxygen species-induced migration and invasion of colorectal cancer cells

Y Lei, K Huang, C Gao, QC Lau, H Pan, K Xie… - Molecular & Cellular …, 2011 - ASBMB
… are found in a colorectal cancer-derived metastatic cell line (… their functional roles in colorectal
cancer metastasis. Molecular and … migration and invasion of colorectal cancer cells. Taken …

The colorectal cancer microbiota alter their transcriptome to adapt to the acidity, reactive oxygen species, and metabolite availability of gut microenvironments

MTF Lamaudière, R Arasaradnam, GD Weedall… - Msphere, 2023 - Am Soc Microbiol
… has the genetic potential to drive colorectal cancer onset and progression; however, the …
-damaging reactive oxygen species, which drive colorectal cancer, is compromised in cancer. …