… ROS in the lung may predispose individuals to lung diseases. In this review, we discuss
mechanisms of oxidant stress in the lung, the role of oxidants in lung disease pathogenesis and …

… a central role for oxygen free radicals in the initiation of cellular injury that leads to the
development of several lung diseases (1-3). It is well established that oxygen free radicals and …

Reactive oxygen species (ROS) are involved in numerous physiological and pathophysiological
responses. Increasing evidence implicates ROS as signaling molecules involved in the …

… hydrogen peroxide, and singlet oxygen, are generated not only … oxygen consumption and
production of O•J, H2O2, and NO leading to acute inflammation and HO• generation in the lung…

… Cell-derived reactive oxygen species … damage associated with various chronic inflammatory
lung diseases. Reactive oxygen species are generated intracellularly from several sources, …

… for clinical use in the treatment of lung disease including COPD and ARDS. Several studies
… In a mouse model of LPS-induced acute lung injury, MSCs administration into the lung …

… Reactive oxygen species upregulate the transcription rate of the PAI-1 gene by activating
mitogen-activated protein kinase pathways and/or the NF-kB pathway. PAI-1 plays a pivotal …

… oxygen species and asbestos-associated diseases. First, it is important to demonstrate that
active oxygen species … death in rat lung fibroblasts of active oxygen species. Environ. Res. …

… reactive oxygen species by various lung … oxygen species are produced by multiple
mechanisms in all cell compartments and play a significant role in the pathogenesis of lung diseases …

… oxygen species (ROS)-dependent lung diseases, such as lung fibrosis, asbestos, chronic
airway diseases and lung … lung diseases that currently have no effective treatment options. …