Sex-specific effects of stress on oxytocin neurons correspond with responses to intranasal oxytocin

MQ Steinman, N Duque-Wilckens, GD Greenberg… - Biological …, 2016 - Elsevier
… effects on the activity of OT neurons in female mice but not male mice. In the BNSTmv, … of
OT immunoreactive neurons, and OT/c-fos colocalizations in female mice regardless of social …

Plasticity of neural connections underlying oxytocin-mediated parental behaviors of male mice

K Inada, M Hagihara, K Tsujimoto, T Abe, A Konno… - Neuron, 2022 - cell.com
oxytocin neurons as the key regulators of the parental caregiving behaviors of male mice. We
… the lateral hypothalamus to the oxytocin neurons to be drastically strengthened when male

Oxytocin neurons enable melanocortin regulation of male sexual function in mice

E Semple, F Shalabi, JW Hill - Molecular neurobiology, 2019 - Springer
… We hypothesized that oxytocin neurons may mediate MC4R-driven sexual behavior in
male mice. We therefore examined the ability of MC4Rs on Sim1 and oxytocin neurons to …

An obligate role of oxytocin neurons in diet induced energy expenditure

Z Wu, Y Xu, Y Zhu, AK Sutton, R Zhao, BB Lowell… - 2012 - journals.plos.org
… Our results show that oxytocin neuron ablation in adult … Interestingly, male mice lacking
oxytocin neurons are more … results showing that mice that lack oxytocin neurons develop obesity …

The oxytocin system of mice and men—similarities and discrepancies of oxytocinergic modulation in rodents and primates

F Althammer, G Jirikowski, V Grinevich - Peptides, 2018 - Elsevier
… In humans, OT neurons have been reported to project to various brain areas including BNST…
the total population of OT neurons seems to be comparable in males and females, and does …

Oxytocinoxytocin receptor systems facilitate social defeat posture in male mice

N Nasanbuyan, M Yoshida, Y Takayanagi… - …, 2018 - academic.oup.com
… Here, we first examined whether social defeat stress activates oxytocin neurons in the
hypothalamus and BNST in mice and then whether social defeat stress activates …

The impact of oxytocin gene knockout on sexual behavior and gene expression related to neuroendocrine systems in the brain of female mice

JM Zimmermann-Peruzatto, VM Lazzari… - Cellular and molecular …, 2017 - Springer
… In addition, OTKO male exhibited an overactivation in the somatosensory cortex and HPC
detected by Fos immunoreactivity in these areas when compared to the WT mice, while in the …

Social stimuli induce activation of oxytocin neurons within the paraventricular nucleus of the hypothalamus to promote social behavior in male mice

SL Resendez, VMK Namboodiri, JM Otis… - Journal of …, 2020 - Soc Neuroscience
… that a mouse model of ASD (Shank3b KO mice) has reduced numbers of PVH-OT neurons.
Importantly, well characterized deficits in the social behavior of Shank3b KO mice (Peça et al.…

Morpho-electric properties and diversity of oxytocin neurons in paraventricular nucleus of hypothalamus in female and male mice

S Chen, H Xu, S Dong, L Xiao - Journal of Neuroscience, 2022 - Soc Neuroscience
… As both male and female mice were used in this study, we separately investigated the … (Table
2) OXT neurons. For both Magno and Parvo OXT neurons, no significant differences were …

Vasopressin stimulates ventromedial hypothalamic neurons via oxytocin receptors in oxytocin gene knockout male and female mice

AK Ragnauth, A Goodwillie, C Brewer, LJ Muglia… - …, 2004 - karger.com
… the behaviors of these mice did not … male and female OTKO mice and their wild-type littermate
to test two hypotheses about OT functional genomics. First, we proposed that in OTKO mice