… PTX-induced peripheral neuropathic pain. To further assess whether these findings were
mediated by peripheral OXTR activation, we tested the effects of the OXTR selective agonist …

… or peripheral oxytocin administration attenuates the pain-like behavior in a well-established
model of neuropathic pain. … the therapeutic relevance of oxytocin in chronic pain conditions. …

… pain. In this review, we present a summary of the total literature related to the effects of oxytocin
on pain … of oxytocin in pain may highlight novel mechanisms associated with analgesia. …

… activate their receptors, OXTR or AVPR1A, expressed in the termini of peripheral nociceptors,
… a non-canonical oxytocin receptor, is also downregulated by direct oxytocin binding. Many …

… It is well documented that central oxytocin (OXT) and oxytocin receptor (OXTR) play roles
in analgesia[16-18]. However, the peripheral expression of OXTRin DRG and the analgesic …

… of oxytocin, atosiban (an oxytocin receptor antagonist) and naloxone (an opioid receptor
antagonist) into the VLOC on spared nerve injury (SNI)-induced neuropathic pain. In addition, …

… injury in rodents is mechanical hypersensitivity, yet neuropathic pain in humans is as often
… Finally, we were unable to assess oxytocin receptors anatomically using immunostaining, …

… An accumulating body of evidence suggests that the hypothalamic neuropeptide oxytocin
(OT) has a modulatory effect on pain processing. Particularly strong evidence comes from …

… oxytocin (OXT)-induced analgesic effect on orofacial neuropathic pain following infraorbital
nerve … IONI was established through tight ligation of one-third of the infraorbital nerve …

… We hypothesized that the antinociceptive effect of OT on neuropathic pain may … neuropathic
pain. Methods: Partial sciatic nerve ligation (pSNL) was performed to induce neuropathic …