p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice
WG Smalley-Freed, A Efimov… - The Journal of …, 2010 - Am Soc Clin Investig
… Its function is regulated in part by p120-catenin (referred to herein as p120), a cytoplasmic
… effect of p120 deficiency in mouse small intestine and colon. p120 conditional KO mice were …
… effect of p120 deficiency in mouse small intestine and colon. p120 conditional KO mice were …
p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia
… Here, using conditional p120 knockout in Apc-sensitized mouse models of intestinal … p120
loss in the intestine, we previously developed a TAM regime in p120 fl/fl ; Villin CreERT2 mice …
loss in the intestine, we previously developed a TAM regime in p120 fl/fl ; Villin CreERT2 mice …
Adenoma formation following limited ablation of p120-catenin in the mouse intestine
… Previously, we reported that p120 is essential in the intestine for … our p120 conditional
knockout mouse, we evaluated the effects of targeted p120 ablation in the small intestine and colon…
knockout mouse, we evaluated the effects of targeted p120 ablation in the small intestine and colon…
p120-catenin regulates WNT signaling and EMT in the mouse embryo
R Hernández-Martínez, N Ramkumar… - Proceedings of the …, 2019 - National Acad Sciences
… p120-catenin may play an important role in EMTs. Here, we describe the role of p120-catenin
in mouse … in some tumors: For example, mosaic deletion of p120 in the intestine leads to …
in mouse … in some tumors: For example, mosaic deletion of p120 in the intestine leads to …
p120-catenin in cancer–mechanisms, models and opportunities for intervention
RCJ Schackmann, M Tenhagen… - Journal of cell …, 2013 - journals.biologists.com
… knockout of p120 in mice was recently linked to tumor formation, indicating that p120 can
also … Intriguingly, when reverting to mosaic p120 deletion in the mouse small intestine, the …
also … Intriguingly, when reverting to mosaic p120 deletion in the mouse small intestine, the …
[HTML][HTML] p120-catenin: Past and present
AB Reynolds - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2007 - Elsevier
… Of particular interest are in vivo transgenic studies in the intestine … Studies using direct
p120-ablation in mice are underway to … of targeted p120 ablation in mice will reveal whether p120-…
p120-ablation in mice are underway to … of targeted p120 ablation in mice will reveal whether p120-…
[HTML][HTML] p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas
… the biology of p120 catenin in pancreas development, we ablated p120 catenin in mouse
pancreatic progenitor cells, which resulted in deletion of p120 catenin in all epithelial lineages …
pancreatic progenitor cells, which resulted in deletion of p120 catenin in all epithelial lineages …
The homeodomain transcription factors Cdx1 and Cdx2 induce E-cadherin adhesion activity by reducing β-and p120-catenin tyrosine phosphorylation
T Ezaki, RJ Guo, H Li, AB Reynolds… - … -Gastrointestinal and …, 2007 - journals.physiology.org
… robust p120-catenin/E-cadherin interactions. We specifically investigated β- and p120-catenin
for … We restored β- and p120-catenin tyrosine phosphorylation in Cdx2-expressing cells by …
for … We restored β- and p120-catenin tyrosine phosphorylation in Cdx2-expressing cells by …
p120-Catenin is required for mouse vascular development
RG Oas, K Xiao, S Summers, KB Wittich… - Circulation …, 2010 - Am Heart Assoc
… of p120 in mammalian vascular development by generating a conditionally mutant mouse
lacking endothelial p120 … deletion strategy was used to ablate p120 expression, using the Tie2 …
lacking endothelial p120 … deletion strategy was used to ablate p120 expression, using the Tie2 …
p120 catenin suppresses basal epithelial cell extrusion in invasive pancreatic neoplasia
AM Hendley, YJ Wang, K Polireddy, J Alsina, I Ahmed… - Cancer research, 2016 - AACR
… Pdx1 ; p120 f/f mice, we reported that p120 catenin is required … To determine the function of
p120 catenin in adult mouse … transgenic mice harboring floxed alleles of p120 catenin (p120 …
p120 catenin in adult mouse … transgenic mice harboring floxed alleles of p120 catenin (p120 …
相关搜索
- p120 catenin mouse vascular development
- p120 catenin barrier function
- β catenin mouse development
- p120 catenin intestinal neoplasia
- p120 catenin colon adenocarcinoma cells
- p120 catenin mouse salivary gland
- p120 catenin isoforms
- sporadic activation β catenin in mice
- p120 catenin mouse embryo
- role of p120 catenin
- p120 catenin tyrosine phosphorylation
- p120 catenin cadherin turnover
- p120 catenin e-cadherin function
- p120 catenin adenoma formation
- p120 catenin opportunities for intervention
- p120 catenin inflammation and cancer