… : HPV-induced penile cancers overexpress p16ink4a, HPV-negative cancers associated with dermatoses express p53, but lack p16ink4a overexpression

S Mannweiler, S Sygulla, E Winter… - Journal of the American …, 2013 - Elsevier
… showed that p16 ink4a overexpression in penile preinvasive and invasive cancer correlated
… demonstration of p16 ink4a overexpression can safely identify penile lesions as HPV-HR …
被引用次数：117 相关文章 所有 7 个版本

Prevalence of human papillomavirus DNA and p16INK4a in penile cancer and penile intraepithelial neoplasia: a systematic review and meta-analysis

TB Olesen, FL Sand, CL Rasmussen, V Albieri… - The lancet …, 2019 - thelancet.com
… in penile intraepithelial neoplasia or p16 INK4a percent positivity in penile cancer and penile
… and p16 INK4a positivity in penile cancer and penile intraepithelial neoplasia worldwide. …
被引用次数：217 相关文章 所有 13 个版本

Value of p16INK4a in the pathology of invasive penile squamous cell carcinomas: a report of 202 cases

AL Cubilla, B Lloveras, M Alejo, O Clavero… - The American journal …, 2011 - journals.lww.com
… p16 INK4a overexpression was found to be a reliable marker for HR-HPV and a helpful
tool in the differential diagnosis of low-grade verruciform and high-grade solid penile tumors. …
被引用次数：122 相关文章 所有 5 个版本
[PDF] academia.edu

Human papillomavirus infection and immunohistochemical p16INK4a expression as predictors of outcome in penile squamous cell carcinomas

SM Bezerra, A Chaux, MW Ball, SF Faraj, E Munari… - Human pathology, 2015 - Elsevier
… ) detection with clinicopathological features of penile carcinoma as well as correlate the findings
… between HR-HPV ISH positivity and p16 INK4a overexpression and outcome in a single-…
被引用次数：56 相关文章 所有 10 个版本
[HTML] plos.org

[HTML][HTML] P16INK4a expression in patients with penile cancer

VA Martins, JD Pinho, AAL Teixeira Júnior… - PloS one, 2018 - journals.plos.org
… In the present study, expression of the p16 INK4a protein was only associated with tumor
subtype, with p16 INK4a overexpression observed in all cases. However, no association was …
被引用次数：37 相关文章 所有 11 个版本

Lack of P16ink4a over expression in penile squamous cell carcinoma is associated with recurrence after lymph node dissection

DH Tang, PE Clark, G Giannico, O Hameed… - The Journal of …, 2015 - Elsevier
… In this study we detected P16 ink4a over expression in 49.5% of penile squamous cell
carcinoma cases. This frequency is slightly higher than that reported by Ferrándiz-Pulido 18 and …
被引用次数：29 相关文章 所有 5 个版本
[PDF] pagepressjournals.org

Prognostic value of p16INK4a overexpression in penile cancer

M Pereira-Lourenço, DV e Brito… - Archivio Italiano di …, 2020 - pagepressjournals.org
… between expression of p16INK4a and HPV infection in penile cancer is still … in penile cancer.
Other goals are to evaluate the epidemiologic association between HPV and penile cancer …
被引用次数：5 相关文章 所有 8 个版本
[HTML] nih.gov

Clinical significance of p53 and p16ink4a status in a contemporary North American Penile Carcinoma Cohort

K Zargar-Shoshtari, PE Spiess, AE Berglund… - … genitourinary cancer, 2016 - Elsevier
… of p16 ink4a in HPV-infected cells. Immunohistochemical staining can detect the overexpression
of p16 ink4a … p16 ink4a overexpression is only seen in high-risk HPV genotypes.1, 2 …
被引用次数：43 相关文章 所有 7 个版本

Alterations in the tumor suppressor gene p16 INK4A are associated with aggressive behavior of penile carcinomas

M Poetsch, M Hemmerich, C Kakies, B Kleist, E Wolf… - Virchows Archiv, 2011 - Springer
… In this study, p53 overexpression was seen in about one third of penile tumors with and
without HPV DNA. There was no significant difference in p53 expression in HPV-DNA positive or …
被引用次数：101 相关文章 所有 11 个版本
[HTML] plos.org

[HTML][HTML] Presence of HPV with overexpression of p16INK4a protein and EBV infection in penile cancer—A series of cases from Brazil Amazon

VCA Martins, IW Cunha, G Figliuolo, HHMF Rondon… - PloS one, 2020 - journals.plos.org
… HPV E7 results in overexpression of p16 INK4a due to the lack of negative feedback loop
between pRb and p16 protein [15]. The overexpression of p16 INK4a in tumor cells has been …
被引用次数：12 相关文章 所有 12 个版本