… In this study we showed that p16 ink4a overexpression in penile … -induced carcinogenesis,
immunohistochemical demonstration of p16 ink4a overexpression can safely identify penile …

… in patients positive for p16INK4a (DFS at 36 … for p16INK4a is smaller than the one found in
literature, which can suggest a less relevant part of HPV infection in the oncogenesis of penile …

… In summary, HPV positivity and p16 INK4a overexpression were significantly associated
with basaloid histologic subtype and presence of lymphovascular invasion. Human …

… Two major pathways of penile carcinogenesis: HPV-induced penile cancers overexpress
p16ink4a, … cancers associated with dermatoses express p53, but lack p16ink4a overexpression …

… for the carcinogenesis of penile cancer. Due to … overexpression in the absence of HPV
infection [27–29]. Our results show that overexpression of p16 is a frequent event also in penile …

… are two pathways related to carcinogenesis: one dependent on … tumor subtype, with p16
INK4a overexpression observed in all … of penile carcinomas showed that p16 INK4a expression …

… in penile intraepithelial neoplasia or p16 INK4a percent positivity in penile cancer and penile
… and p16 INK4a positivity in penile cancer and penile intraepithelial neoplasia worldwide. …

… In this study we detected P16 ink4a over expression in 49.5% of penile squamous cell
carcinoma cases. This frequency is slightly higher than that reported by Ferrándiz-Pulido 18 and …

… leads to accumulation of p16 ink4a in the HPV-infected cells, and overexpression of … pathway
of penile carcinogenesis involves dysregulation of genes in the p16 ink4a /cyclin D/RB and …

… p16 INK4a overexpression was found to be a reliable marker for HR-HPV and a … penile
tumors. SCC variants depicting basaloid features were more likely to be HPV and p16 INK4a …