… Here, we review the function of P2X7 receptor in conditioning T cell-dependent immunity
against cancer. … Influence of P2X7R activity on tumor and immune system cells. (A) In …

… of anti-tumor immunity by the P2X7R resides in the ability to … , that in turn potentiate tumor
antigen presentation by dendritic … of anti-tumor immunity the P2X7R is also involved in immune …

… P2X7 receptor in immunity and inflammation, the role of the P2X7 receptor in tumor immunity
… There were two landmark studies linking the P2X7 receptor with immune-mediated tumor …

… versus pharmacological blockade of the P2X7 receptor also had a … P2X7 receptor is a
crucial determinant of tumor–host interaction since its expression and function affect both immune …

… Immunohistochemistry revealed strong P2X7 positivity in several human cancers. Together,
our findings provide direct evidence that P2X7 promotes tumor growth in vivo. Cancer Res; …

… The P2X7 receptor (P2X7R), a member of the P2XRs subfamily, can function as a cation-…
Given the key role of host P2X7R in the antitumor immune responses highlighted in the …

… The P2X7 receptor has a ubiquitous distribution in nearly all tissues and organs of the body
… expression in immune cells of monocyte-macrophage origin. Cloning of the P2X7 receptor in …

… between P2X7 functions drive tumor progression and immune … downstream of the P2X7
receptor before discussing how the … plays a central role in the regulation of anti-tumor immunity. …

… interaction with its ligands on cancer and immune response, as well as its role in
inflammation and tumour-associated inflammation. We also describe the currently employed …

… tumor immune escape through the conversion of immune … of P2X7 receptor activation and
the immune status in the tumor … is that P2X7 receptor can also promote tumor blood vessel …