Monotherapy with a P2Y12 inhibitor or aspirin for secondary prevention in patients with established atherosclerosis: a systematic review and meta-analysis

M Chiarito, J Sanz-Sánchez, F Cannata, D Cao… - The Lancet, 2020 - thelancet.com
… In this systematic review and meta-analysis, all randomised trials comparing P2Y 12
inhibitor with aspirin monotherapy for secondary prevention in patients with cerebrovascular, …

P2Y12 Inhibitor or Aspirin Monotherapy for Secondary Prevention of Coronary Events

F Gragnano, D Cao, L Pirondini, A Franzone… - Journal of the American …, 2023 - jacc.org
… with currently recommended oral P2Y 12 inhibitors (clopidogrel, prasugrel, or ticagrelor) vs
aspirin monotherapy for the secondary prevention of adjudicated adverse events exclusively …

P2Y12 inhibitor versus aspirin monotherapy for secondary prevention of cardiovascular events: meta-analysis of randomized trials

D Aggarwal, K Bhatia, ZS Chunawala… - … heart journal open, 2022 - academic.oup.com
… In conclusion, in this meta-analysis of randomized trials, P2Y 12 inhibitor monotherapy for
chronic secondary prevention was associated with lower risk of MACE and MI compared with …

P2Y12 receptor inhibitors for secondary prevention of ischemic stroke

F Liu, US Tantry, PA Gurbel - Expert opinion on pharmacotherapy, 2015 - Taylor & Francis
… for the secondary prevention and also duration of therapy. Herein, we aim to provide a
comprehensive review of the role of P2Y 12 receptor inhibitors in the secondary prevention of …

P2Y12 inhibitors plus aspirin for acute treatment and secondary prevention in minor stroke and high-risk transient ischemic attack: A systematic review and meta …

F Pomero, E Galli, M Bellesini, L Maroni… - European Journal of …, 2022 - Elsevier
… This systematic review aimed to compare early use of P2Y12 inhibitors (clopidogrel/ticagrelor)
plus aspirin to aspirin alone for acute treatment and secondary prevention in acute non-…

[HTML][HTML] P2Y12 inhibitor monotherapy: considerations for acute and long-term secondary prevention post-PCI

A Greco, MS Mauro, D Capodanno… - Reviews in …, 2022 - imrpress.com
… in the treatment and secondary prevention of atherosclerotic … strategy for long-term secondary
prevention, a field where … long-term secondary prevention of cardiovascular events in …

P2Y12 inhibitors versus aspirin monotherapy for long-term secondary prevention of atherosclerotic cardiovascular disease events: a systematic review and meta …

A Al-Abdouh, W Abusnina, M Mhanna… - Current problems in …, 2022 - Elsevier
… Our meta-analysis showed that using P2Y 12 inhibitors for secondary prevention of ASCVD
events was associated with lower rates of myocardial infarction and stroke without any …

The Safety and Efficacy of Aspirin Discontinuation on a Background of a P2Y12 Inhibitor in Patients After Percutaneous Coronary Intervention: A Systematic Review …

ML O'Donoghue, SA Murphy, MS Sabatine - Circulation, 2020 - Am Heart Assoc
… controversial, more prolonged use of a P2Y 12 inhibitor on a background of aspirin reduces
risk of recurrent cardiac events in secondary prevention, but increases the risk of bleeding. …

Comparison of aspirin and P2Y12 inhibitors for secondary prevention of ischaemic stroke: a systematic review and meta-analysis

K Zhang, Y Wang, T Liu, X Niu - Current Reviews in Clinical …, 2023 - ingentaconnect.com
… aspirin, P2Y12 inhibitors have been … P2Y12 inhibitors are stronger platelet inhibitors than
aspirin [10, 11]. Several trials comparing P2Y12 inhibitors with aspirin for secondary prevention

Are P2Y12 inhibitors superior to aspirin for long-term secondary prevention of cardiovascular disease?

S Carlin, J Eikelboom - Expert Review of Cardiovascular Therapy, 2023 - Taylor & Francis
… meta-analyses suggest that P2Y12 inhibitors are more effective and … P2Y12 inhibitors
should become the preferred single agent antiplatelet therapy for long-term secondary prevention