Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response
Z Sun, YE Chin, DD Zhang - Molecular and cellular biology, 2009 - Taylor & Francis
… antioxidants and detoxification enzymes are transcriptionally upregulated upon deleterious
oxidative stress through the cis antioxidant … p300/CBP directly acetylates Nrf2 in response to …
oxidative stress through the cis antioxidant … p300/CBP directly acetylates Nrf2 in response to …
[HTML][HTML] Activated histone acetyltransferase p300/CBP-related signalling pathways mediate up-regulation of NADPH oxidase, inflammation, and fibrosis in diabetic …
… mediates the induction of Nox expression in response to pro-inflammatory or diabetic factors,
we hypothesized that p300/CBP could become an additional therapeutic target in DKD to …
we hypothesized that p300/CBP could become an additional therapeutic target in DKD to …
Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity
TB Dansen, LMM Smits, MH Van Triest… - Nature chemical …, 2009 - nature.com
… disulfide–dependent complexes of FoxO and the p300/CBP acetyltransferase, and that
modulation of FoxO biological activity by p300/CBP-mediated acetylation is fully dependent on …
modulation of FoxO biological activity by p300/CBP-mediated acetylation is fully dependent on …
p300/CBP as a key nutritional sensor for hepatic energy homeostasis and liver fibrosis
W Yao, T Wang, F Huang - BioMed Research International, 2018 - Wiley Online Library
… potential roles of p300/CBP in mammalian metabolic homeostasis in response to nutrients.
This review is focused on the different targets and functions of p300/CBP in physiological and …
This review is focused on the different targets and functions of p300/CBP in physiological and …
[HTML][HTML] Inhibition of p300/CBP-associated factor attenuates renal tubulointerstitial fibrosis through modulation of NF-kB and Nrf2
S Chung, S Kim, M Son, M Kim, ES Koh… - International journal of …, 2019 - mdpi.com
… enhanced PCAF could mitigate renal fibrosis by redressing aberrant balance between
inflammatory signaling and antioxidant response through the modulation of NF-κB and Nrf2. …
inflammatory signaling and antioxidant response through the modulation of NF-κB and Nrf2. …
[HTML][HTML] Downregulation of P300/CBP-associated factor protects from vascular aging via Nrf2 signal pathway activation
L Qiu, X Liu, H Xia, C Xu - International Journal of Molecular Sciences, 2022 - mdpi.com
… conserved redox-sensitive transcription factor, which coordinates the antioxidant response
by regulating the transcription of antioxidant factors, including heme oxygenase-1 (HO-1), …
by regulating the transcription of antioxidant factors, including heme oxygenase-1 (HO-1), …
[PDF][PDF] … p300/CBP-Related Signalling Pathways Mediate Up-Regulation of NADPH Oxidase, Inflammation, and Fibrosis in Diabetic Kidney. Antioxidants 2021, 10, 1356
… mediates the induction of Nox expression in response to pro-inflammatory or diabetic factors,
we hypothesized that p300/CBP could become an additional therapeutic target in DKD to …
we hypothesized that p300/CBP could become an additional therapeutic target in DKD to …
[HTML][HTML] Protein lysine acetylation by p300/CBP
… in the antioxidant response), but this was inhibited when p53 was bound to p300/CBP (via
the … used to stimulate glucocorticoid receptor binding to p300/CBP (via the N-terminal nuclear …
the … used to stimulate glucocorticoid receptor binding to p300/CBP (via the N-terminal nuclear …
Viral Mechanisms Involved in the Transcriptional CBP/р300 Regulation of Inflammatory and Immune Responses
Y Revilla, AG Granja - Critical Reviews™ in Immunology, 2009 - dl.begellhouse.com
… the carboxyl terminus of p300/CBP, but have different effects on p300/CBP phosphorylation.…
of p300, thus inhibiting p300/ CBP phosphorylation,45 whereas E1A stimulates p300/CBP …
of p300, thus inhibiting p300/ CBP phosphorylation,45 whereas E1A stimulates p300/CBP …
Valproic acid exposure decreases Cbp/p300 protein expression and histone acetyltransferase activity in P19 cells
CL Lamparter, LM Winn - Toxicology and Applied Pharmacology, 2016 - Elsevier
… attenuated by pre-treatment with the antioxidant catalase. C646 exposure also decreased
NF… adaptive HAT response following VPA exposure and suggests that reduced Cbp/p300 HAT …
NF… adaptive HAT response following VPA exposure and suggests that reduced Cbp/p300 HAT …
相关搜索
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