Understanding MAPK signaling pathways in apoptosis
J Yue, JM López - International journal of molecular sciences, 2020 - mdpi.com
… In addition to regulating the levels of the expression of apoptotic proteins, JNK/p38 MAPK …
and intrinsic apoptotic pathways. The extrinsic pathway, or death-receptor pathway, can …
and intrinsic apoptotic pathways. The extrinsic pathway, or death-receptor pathway, can …
p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents
X Sui, N Kong, LI Ye, W Han, J Zhou, Q Zhang, C He… - Cancer letters, 2014 - Elsevier
… role of p38 and JNK MAPK pathways in regulating the balance of autophagy and apoptosis
will hopefully … In addition to apoptosis, p38 MAPK can also mediate autophagy in response to …
will hopefully … In addition to apoptosis, p38 MAPK can also mediate autophagy in response to …
MAP kinase pathways activated by stress: the p38 MAPK pathway
T Obata, GE Brown, MB Yaffe - Critical care medicine, 2000 - journals.lww.com
… p38 MAPK appears to play a major role in apoptosis, cytokine production, transcriptional
regulation, and cytoskeletal reorganization, and has been causally implicated in sepsis, …
regulation, and cytoskeletal reorganization, and has been causally implicated in sepsis, …
Stress relief techniques: p38 MAPK determines the balance of cell cycle and apoptosis pathways
RH Whitaker, JG Cook - Biomolecules, 2021 - mdpi.com
… among the p38 MAPK, cell cycle, and apoptosis signaling pathways. … pathways and cell
regulatory mechanisms, in this review we focus on the roles that the p38 stress pathway performs …
regulatory mechanisms, in this review we focus on the roles that the p38 stress pathway performs …
Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8-and-9-mediated apoptotic pathways in dopaminergic neurons
WS Choi, DS Eom, BS Han, WK Kim, BH Han… - Journal of Biological …, 2004 - ASBMB
… This neurotoxin-induced phosphorylation of p38 was inhibited in the presence … p38 signal
pathway leading to activation of both mitochondrial and extramitochondrial apoptotic pathways …
pathway leading to activation of both mitochondrial and extramitochondrial apoptotic pathways …
Mechanisms and functions of p38 MAPK signalling
A Cuadrado, AR Nebreda - Biochemical journal, 2010 - portlandpress.com
… In the present review, we provide an overview of the p38 MAPK pathway, which is
strongly … been shown to trigger p38 MAPK activation, including ASK1 (apoptosis signal-regulating …
strongly … been shown to trigger p38 MAPK activation, including ASK1 (apoptosis signal-regulating …
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
Z Xia, M Dickens, J Raingeaud, RJ Davis… - Science, 1995 - science.org
… Role of the p38 MAP kinase signaling pathway in apoptosis. To investigate the importance
of the p38 MAP kinase pathway for apoptosis, we examined whether ectopic expression of …
of the p38 MAP kinase pathway for apoptosis, we examined whether ectopic expression of …
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
… -SEK1 (or MKK4)-SAPK (or JNK) pathways (2, 3, 4, 5, 6… p38 MAPK form another MAPK
signaling unit (2, 8); however, the biological consequence and mechanism of activation of the p38 …
signaling unit (2, 8); however, the biological consequence and mechanism of activation of the p38 …
The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells
Q Zhou, S Wang, H Zhang, Y Lu, X Wang… - Acta Pharmacologica …, 2009 - nature.com
… and baicalein via the ERK/p38 MAPK signaling pathway. … derives from the induction of
apoptosis, which involves activation of … of bax or p53 expression via ERK/p38 MAPK pathway. …
apoptosis, which involves activation of … of bax or p53 expression via ERK/p38 MAPK pathway. …
Activation and signaling of the p38 MAP kinase pathway
T Zarubin, J Han - Cell research, 2005 - nature.com
… apoptotic pathway and are expressed as inactive zymogens 98, 99 . Caspase inhibitors then
can block p38 activation through Fas cross-linking, suggesting p38 … p38 MAPK activity. Also, …
can block p38 activation through Fas cross-linking, suggesting p38 … p38 MAPK activity. Also, …
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