[HTML][HTML] Understanding MAPK signaling pathways in apoptosis

J Yue, JM López - International journal of molecular sciences, 2020 - mdpi.com
… In addition to regulating the levels of the expression of apoptotic proteins, JNK/p38 MAPK
and intrinsic apoptotic pathways. The extrinsic pathway, or death-receptor pathway, can …

MAP kinase pathways activated by stress: the p38 MAPK pathway

T Obata, GE Brown, MB Yaffe - Critical care medicine, 2000 - journals.lww.com
p38 MAPK appears to play a major role in apoptosis, cytokine production, transcriptional
regulation, and cytoskeletal reorganization, and has been causally implicated in sepsis, …

[HTML][HTML] Stress relief techniques: p38 MAPK determines the balance of cell cycle and apoptosis pathways

RH Whitaker, JG Cook - Biomolecules, 2021 - mdpi.com
… among the p38 MAPK, cell cycle, and apoptosis signaling pathways. … pathways and cell
regulatory mechanisms, in this review we focus on the roles that the p38 stress pathway performs …

[HTML][HTML] … of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8-and-9-mediated apoptotic pathways in dopaminergic neurons

WS Choi, DS Eom, BS Han, WK Kim, BH Han… - Journal of Biological …, 2004 - ASBMB
… This neurotoxin-induced phosphorylation of p38 was inhibited in the presence … p38 signal
pathway leading to activation of both mitochondrial and extramitochondrial apoptotic pathways

[HTML][HTML] p38 MAP-kinases pathway regulation, function and role in human diseases

A Cuenda, S Rousseau - Biochimica et Biophysica Acta (BBA)-Molecular …, 2007 - Elsevier
p38 MAPK pathways appears to be cell type and stimulus specific. Several MKKKs have been
implicated in the regulation of p38 MAPK … of the p38α pathway that lead to apoptosis and …

The p38 MAP kinase pathway and its biological function

L New, J Han - Trends in cardiovascular medicine, 1998 - Elsevier
… Thus, the p38 MAP kinase cascade may consist of the … other potential regulators of the p38
pathway have been defined. … Therefore, the involvement of p38 isoforms in apoptosis may …

p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

X Sui, N Kong, LI Ye, W Han, J Zhou, Q Zhang, C He… - Cancer letters, 2014 - Elsevier
… role of p38 and JNK MAPK pathways in regulating the balance of autophagy and apoptosis
will hopefully … In addition to apoptosis, p38 MAPK can also mediate autophagy in response to …

Mapping out p38 MAPK

EA Bonney - American Journal of Reproductive Immunology, 2017 - Wiley Online Library
… The two major apoptotic pathways that are well documented in mammalian cells are the …
the mitochondrial pathway in the death receptor pathway. The death receptor pathway involves …

Mechanisms and functions of p38 MAPK signalling

A Cuadrado, AR Nebreda - Biochemical journal, 2010 - portlandpress.com
… In the present review, we provide an overview of the p38 MAPK pathway, which is
strongly … been shown to trigger p38 MAPK activation, including ASK1 (apoptosis signal-regulating …

[HTML][HTML] Activation and signaling of the p38 MAP kinase pathway

T Zarubin, J Han - Cell research, 2005 - nature.com
apoptotic pathway and are expressed as inactive zymogens 98, 99 . Caspase inhibitors then
can block p38 activation through Fas cross-linking, suggesting p38p38 MAPK activity. Also, …