… underlying TNF-α-induced apoptosis in NSCs. Our research demonstrates the role of p38
MAPK as a novel apoptotic signal during TNF-α-induced apoptosis in NSCs. Moreover, our …

… To examine the role of JNK, p38 MAPK and ERK in Aplidin ™ induced apoptosis, we tested
the effect of the MAPK pathways inhibitors curcumin (JNK inhibitor), SB203580 (p38 inhibitor…

… p38 signaling pathways contribute to induction of apoptosis … -7 Since activated MAPKs
play a critical role in apoptosis, we … of MAPK family members including ERK, JNK and p38. As …

… p38 MAPK in TNF-induced endothelial apoptosis. Our results suggest that p38 MAPK mediates
TNF-induced apoptosis … It has also been discovered that activation of apoptotic pathways …

… cardiac recovery, decreased infarct size, and reduced apoptosis [66]. This was related to …
and block the activation of p38 and JNK, thus reducing apoptosis during ischemia–reperfusion […

… by p38 inhibition. This study provides the first example whereby p38 induces apoptosis by
… may be a common regulatory point for cell death induced by both JNK and p38 pathways. …

… to escape the apoptotic challenge. this study assessed whether the p38 MaPK pathway is
… 5-fu only or 5-fu combined with a p38 MaPK pathway inhibitor (SB203580) was used to treat …

… of three major MAPKs in the apoptosis specifically … p38 MAPK is a component of the
GC-evoked pathway to lymphoid cell apoptosis in human and mouse cell systems and that the p38-…

… here that p38 MAPK predominantly mediates γ-irradiation-induced HDMEC apoptosis.
HDMECs treated with VEGF were markedly resistant to γ-irradiation-mediated apoptosis. This …

… -SEK1 (or MKK4)-SAPK (or JNK) pathways (2, 3, 4, 5, 6… p38 MAPK form another MAPK
signaling unit (2, 8); however, the biological consequence and mechanism of activation of the p38 …