[HTML][HTML] Non-classical p38 map kinase functions: cell cycle checkpoints and survival

TM Thornton, M Rincon - International journal of biological …, 2009 - ncbi.nlm.nih.gov
… Here we discuss the role of p38 MAPK in the mediation of cell cycle checkpoints and cell
survival, … We describe how p38 MAPK regulates both the G2/M as well as a G1/S cell cycle

Cell cycle regulation by p38 MAP kinases

C Ambrosino, AR Nebreda - Biology of the Cell, 2001 - Elsevier
p38 MAP kinase pathway arrests cell cycle progression and the differentiation process.
Immature thymocytes are probably arrested early in mitosis and contain higher levels of cyclin A. …

Stress relief techniques: p38 MAPK determines the balance of cell cycle and apoptosis pathways

RH Whitaker, JG Cook - Biomolecules, 2021 - mdpi.com
… , and the balance of binding between these two sides determines cell survival. Here, we
discuss the intersections among the p38 MAPK, cell cycle, and apoptosis signaling pathways. …

p38 MAPK in development and cancer

C Bradham, DR McClay - Cell cycle, 2006 - Taylor & Francis
… , p38 was shown to induce apoptosis in some cells, but prevent apoptosis in others. Similarly
opposed effects had been observed with respect to cell cycle regulation. The role of p38 in …

p38 MAPK activation, DNA damage, cell cycle arrest and apoptosis as mechanisms of toxicity of silver nanoparticles in Jurkat T cells

HJ Eom, J Choi - Environmental science & technology, 2010 - ACS Publications
… Of the MAPK tested, the expression of p-p38 MAPK protein increased on exposure to … the
cells exposed to 0.2 mg/L of AgNPs (Figure 2A). A temporal analysis revealed that p-p38 MAPK

p38MAPK controls expression of multiple cell cycle inhibitors and islet proliferation with advancing age

ESM Wong, X Le Guezennec, ON Demidov… - Developmental cell, 2009 - cell.com
… ), specifically attenuates p38MAPK signaling without an effect on other MAPK pathways. In
… (A) Activation of p38 MAPK was analyzed in the pancreas obtained from young and old WT …

Distinct roles for phosphoinositide 3-kinase, mitogen-activated protein kinase and p38 MAPK in mediating cell cycle progression of breast cancer cells

RM Neve, T Holbro, NE Hynes - Oncogene, 2002 - nature.com
cells, we show here that HRG induction of cell cycle progression requires activation of MAPK,
PI3K and p38MAPK … These pathways are known to regulate cell cycle components at the …

Activation of p38 MAPK induces cell cycle arrest via inhibition of Raf/ERK pathway during muscle differentiation

J Lee, F Hong, S Kwon, SS Kim, DO Kim… - Biochemical and …, 2002 - Elsevier
cell line and Hep3 human carcinoma cells [21], [22]. In the present study, we investigated
whether p38 MAPK is involved in cell cycle … We showed that p38 MAPK inhibits the Raf/ERK …

Tetrahydrocurcumin induces G2/M cell cycle arrest and apoptosis involving p38 MAPK activation in human breast cancer cells

N Kang, MM Wang, YH Wang, ZN Zhang… - Food and chemical …, 2014 - Elsevier
… arrest and apoptosis via p38 MAPK in human breast cancer MCF-7 cells. THC inhibited the
… The roles of p38 MAPK in THC-induced apoptosis and G2/M cell cycle arrest in MCF-7 cells. …

PEITC induces G1 cell cycle arrest on HT-29 cells through the activation of p38 MAPK signaling pathway

KL Cheung, TO Khor, S Yu, ANT Kong - The AAPS journal, 2008 - Springer
… through MAPK pathway in prostate and colon cancer cells. In the … of PEITC on cell cycle
regulation of HT-29 colon cancer cells. … G1 cell cycle arrest in HT-29 cells. We showed that the …