Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system

K Takeda, H Ichijo - Genes to Cells, 2002 - Wiley Online Library
… including neuronal cells (Martin-Blanco 2000; Nebreda & Porras 2000; Ono & Han 2000).
In … of p38 signalling in neuronal cell fate decision, in light of analyses using mammalian cell

Antagonistic control of cell fates by JNK and p38-MAPK signaling

T Wada, E Stepniak, L Hui, A Leibbrandt… - Cell Death & …, 2008 - nature.com
… assess functional hierarchies and potential molecular cross-talks between the JNK and
p38-MAPK stress pathways in cell fate decisions, we tested the effects of p38-MAPK modulation …

MAP3Ks as central regulators of cell fate during development

EA Craig, MV Stevens, RR Vaillancourt… - … dynamics: an official …, 2008 - Wiley Online Library
… TAK-1 activates the p38 MAPK and JNK signaling pathways. Conventional disruption of the
… of hepatocytes and hematopoietic cells, suggesting a crucial role for TAK-1 in cell survival. …

p38 MAPK signalling cascades: ancient roles and new functions

E Martín‐Blanco - Bioessays, 2000 - Wiley Online Library
… Additionally, it appears to exert other fundamental roles during development, in cell fate
specification in imaginal discs, and in cell polarity during oogenesis. These functions involve …

MAPKs as mediators of cell fate determination: an approach to neurodegenerative diseases

M Miloso, A Scuteri, D Foudah… - Current medicinal …, 2008 - ingentaconnect.com
… the MAPK pathways since MAPKsMAPK requirements in neural cell fate determination,
focusing our attention on the proliferation and differentiation of NSCs and neural progenitor cells

Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling

A Matsuzawa, H Ichijo - Biochimica et Biophysica Acta (BBA)-General …, 2008 - Elsevier
… of cell function by the MAPK cascade with special focus on the ASK1-MAPK pathway, and we
… activation and physiological functions of ASK1 signaling in stress and immune responses. …

Systematic analysis of the MAPK signaling network reveals MAP3K-driven control of cell fate

AF Peterson, K Ingram, EJ Huang, J Parksong… - Cell systems, 2022 - cell.com
MAPK activity biosensors to investigate how cell fate control emerges from the connectivity
and dynamics of the MAPK … systematically explore the outputs and functions of all the MAP3 …

Regulation of muscle stem cell functions: a focus on the p38 MAPK signaling pathway

J Segalés, E Perdiguero… - Frontiers in cell and …, 2016 - frontiersin.org
cell functional decline with aging. In particular, our review will focus on the epigenetic changes
underlying fate decisions and on how the p38 MAPK … up satellite cell adaptive responses …

Integrated activation of MAP3Ks balances cell fate in response to stress

AM Winter‐Vann, GL Johnson - Journal of cellular biochemistry, 2007 - Wiley Online Library
… of MAPK activation with physiological responses to different stimuli. In this prospective, we
describe the role of different MAP3Ks in the control of MAPK networks, primarily JNK and p38, …

[HTML][HTML] UV-induced interaction between p38 MAPK and p53 serves as a molecular switch in determining cell fate

X Gong, A Liu, X Ming, P Deng, Y Jiang - FEBS letters, 2010 - Elsevier
… that the functional relationship between p38 and p53 is crucial in defining the cell fate after
DNA … In this report, p38 or p53 gene knockout cell lines are employed to study their roles in …