[HTML][HTML] A glance of p53 functions in brain development, neural stem cells, and brain cancer

Y Xiong, Y Zhang, S Xiong, AE Williams-Villalobo - Biology, 2020 - mdpi.com
role of p53 in brain development, neural stem cell regulation and the mechanisms of inactivating
p53p53′s functions in brain development and neural stem cell regulation, as well as …

Novel perspectives on p53 function in neural stem cells and brain tumors

SM Hede, I Nazarenko, M Nistér… - Journal of …, 2011 - Wiley Online Library
… tumor stem cells, … p53 in brain tumors and neural stem cells. Specifically, we review the
literature regarding transformation of adult neural stem cells and, we discuss how the loss of p53

p53 suppresses the self-renewal of adult neural stem cells

K Meletis, V Wirta, SM Hede, M Nistér, J Lundeberg… - 2006 - journals.biologists.com
… the function of p53 in neural stem cells in the adult brain, and report that it acts as a negative
regulator of neural stem cell … To assess a potential role for p53 in the adult neural stem cell

Hedgehog controls neural stem cells through p53‐independent regulation of Nanog

A Po, E Ferretti, E Miele, E De Smaele… - The EMBO …, 2010 - embopress.org
… Consistent with the notion that Nanog may confer stemness features to somatic cells, we also
show that Nanog is upregulated in Hh‐promoted neuronal tumors, specifically featuring the …

p53 regulates the self-renewal and differentiation of neural precursors

A Armesilla-Díaz, P Bragado, I Del Valle, E Cuevas… - Neuroscience, 2009 - Elsevier
… the role of p53 in OB neural progenitor cells by comparing neurosphere cultures obtained
from p53 knockout (p53KO) and p53 wild … We observed that lack of p53 promotes neurosphere …

p53 regulates neural stem cell proliferation and differentiation via BMP-Smad1 signaling and Id1

H Liu, D Jia, A Li, J Chau, D He, X Ruan… - Stem cells and …, 2013 - liebertpub.com
Neural stem cells (NSCs) play essential roles in nervous … Here we present evidence that
tumor suppressor p53 regulates NSC … p53 deficiency led to increased neurogenesis in vivo, and …

Cross talk between cellular redox status, metabolism, and p53 in neural stem cell biology

K Forsberg, S Di Giovanni - The Neuroscientist, 2014 - journals.sagepub.com
… in stem cell quiescence and fate commitment. Here, we explore the known and putative
functions of p53 … reactive oxygen species, p53, and related cellular signaling may regulate NSC …

A GLI1‐p53 inhibitory loop controls neural stem cell and tumour cell numbers

B Stecca, A Ruiz i Altaba - The EMBO journal, 2009 - embopress.org
… We suggest a role for endogenous Gli1 in neural stem cells as enhanced GLI1 levels expand
the number of clonogenic stem cells, and Prominin1 + stem cells from DT +dox cerebella …

[HTML][HTML] p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids

A Marin Navarro, RJ Pronk, AT van der Geest… - Cell death & …, 2020 - nature.com
neural stem cell function to in vitro cortical neurogenesis, we show that p53 aids in proper
neural stem cellfunction. Taken together, our 2D and 3D models derived from human iPS …

[HTML][HTML] p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation

S Sola, JM Xavier, DM Santos, MM Aranha… - PLoS …, 2011 - journals.plos.org
… Mouse neural stem cells used in this study were obtained from Dr. Reynold's Laboratory
at the University of Queensland, Brisbane, Australia, and provided by Dr. Low's Laboratory at …