过去一年中添加的文章，按日期排序

Protein Phosphatase 2ACα Regulates ATR-Mediated Endogenous DNA Damage Response Against Microcephaly

L Lin, J Ding, S Liu, C Liu, Q Li, X Gao, Y Niu… - Molecular …, 2024 - Springer
4 天前 - … P53, P21, Bcl2, and Bax, which led to decreased proliferation of cortical
progenitor cells … Neuroprogenitor cells were cultured in neural stem cell (NSC) medium (DMEM-NutMix, …
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[PDF] usal.es

Influences of Umbilical Cord Mesenchymal Stem Cells and Their Exosomes on Tumor Cell Phenotype

L Guoqing - 2024 - gredos.usal.es
7 天前 - … by oxidative stress, and the NF-κB/P53 signaling pathway is implicated. These
findings provide preliminary evidence that stem cells and their exosomes may not be suitable for …
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[PDF] biorxiv.org

Alcohol induces p53-mediated apoptosis in neural crest by stimulating the AMPK-mediated suppression of TORC1, p70/S6K, and ribosomal biogenesis.

Y Huang, GR Flentke, SM Smith - bioRxiv, 2024 - biorxiv.org
8 天前 - … deletion of craniofacial progenitors, a stem cell lineage called the neural crest (NC).
We … (RBG) and this suppression is causative in their p53/MDM2-mediated apoptosis. Here, …
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… INITIATION, PROGRESSION, AND RESISTANCE: A COMPREHENSIVE APPROACH LEVERAGING BULK MULTIOMICS DECONVOLUTION AND SINGLE-CELL …

P Patel, S Ryall, B Kukreja, A Turinski… - Neuro …, 2024 - ncbi.nlm.nih.gov
22 天前 - … These epigenetic modifications hint at pivotal roles in DMG pathogenesis, yet
effective therapeutic strategies remain elusive, with median survival rates stagnant at …
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MDB-76. ONC201 INHIBITS THE CHARACTERISTICS OF CANCER STEM CELLS IN GROUP 3 MEDULLOBLASTOMA

L Abballe, C Antonacci, M Gianesello, C Lago… - Neuro …, 2024 - ncbi.nlm.nih.gov
22 天前 - … To understand the involvement of the UPR in stem cell maintenance, we have …
ONC201 is an imipridone compound that activates p53-independent apoptosis causing …
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MDB-106. MEDULLOBLASTOMA TUMOR MICROENVIRONMENTS SHOW INTRA-AND INTER-TUMORAL HETEROGENEITY ON SPATIAL TRANSCRIPTOMICS

F Chien, M Michaud, M Bakhtiari, JL Ross… - Neuro …, 2024 - ncbi.nlm.nih.gov
22 天前 - … In addition, molecular pathways known in medulloblastoma, including NF-kB and
TP53 regulatory pathways, were also enriched. Neighborhood-enrichment analysis reveals …
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… PROGENITOR CELL RESCUE (HDCT) DECREASES THE DEVELOPMENT OF CHOROID PLEXUS CARCINOMA (CPC)-SPECIFIC RELAPSE IN HIGH-RISK TP53 …

M Yankelevich, DS Ozorio, W Zaky… - Neuro …, 2024 - ncbi.nlm.nih.gov
22 天前 - … TP53 function defines unfavorable disease. CPC-free survival rates have remained
poor in patients with TP53 … numbers and incomplete TP53 mutation data. Consequently, the …
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STEM-03. A NOVEL MOUSE MODEL OF CHOROID PLEXUS CARCINOMA UNRAVELS SEQUENTIAL DEDIFFERENTIATION OF HINDBRAIN CHOROID PLEXUS …

LS Peter, L Altendorf, K Hack, V Thaden, C Göbel… - Neuro …, 2024 - ncbi.nlm.nih.gov
22 天前 - … of TP53 and overexpression of MYCN and Gli2 in central nervous system precursors
(hGFAP-cre::P53 Fl/… In vitro studies revealed rapidly growing tumor cells with stem cell-like …
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ETMR-26. MIR-34/449 FAMILY PLAYS A CRUCIAL ROLE IN CHOROID PLEXUS MULTICILIATION AND TUMORIGENESIS

N Guru, A Zaman, M Umer, M Zahran, A Siluveru… - Neuro …, 2024 - ncbi.nlm.nih.gov
22 天前 - … Additionally, most CPC in humans carry mutations in TP53 tumor suppressor. …
activity and multiciliated cells in CP organoid derived from human induced pluripotent stem cells. …
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[PDF] j-morphology.com

Protein p53 regulator of apoptosis and cell proliferation

VN Kotov, MG Kostyaeva, SS Ibadullaeva… - Morphology, 2024 - j-morphology.com
24 天前 - … , p53 is involved in the embryogenesis of nervous tissue and promotes the differentiation
of neural stem cells; on the other hand, p53 … on the structure and function of the main …
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