… (IDH) concurrently with P53 and ATRX loss. To model LGA formation, we introduced
R132H IDH1, P53 shRNA, and ATRX shRNA into human neural stem cells (NSCs). These …

… We hypothesized that p53 could play a role in the enhanced stem cell … p53 mRNA expression
in primitive Lin – Sca-1 + c-Kit + (LSK) cells and in various myeloid progenitor cells (CMP, …

… Here, we have identified the role of miR-34a in regulating mouse neural stem (NS) cell …
a foundation for the role of miR-34a in neural stem cell differentiation, the role of p53 in this …

… The tumor suppressor gene product p53 possesses a dual role in cell fate determination;
cell cycle arrest by inducing expression of growth suppressor proteins, such as the cdk inhibitor …

… to the activation of p53, we also examined whether treatment with the p53 inhibitor, PFT-α, …
OGD injury 31 and p53-null neural stem/progenitor cells showed an increased number of …

… of neural stem/progenitor cells (NPCs). However, distinct function of each family member
was reported in regulating stem cells within and without the brain. Hence, to investigate the …

… the p53 signaling pathway. TLX regulates p21 expression in a p53-dependent manner, and
acute removal of p53 can … through genetic interaction with p53 and other signaling pathways. …

… ventricle wall and is supported by a population of neural stem cells (NSCs, also known as
B1 cells). B1 cells divide slowly and can hence retain exogenously administered traceable …

… , and survival of neural stem cells (NSCs). The present study tests the hypothesis that the
EtOH-induced DNA damage response is mediated through p53 pathways and influenced by …

… of increased p53 activity on adult neural stem cells and their … the immature neuronal marker,
doublecortin (DCX), and neuron-… adult neural stem cells, we confirmed that neural stem cells …