… insensitivity to pain, who feel neither pain nor itch, and rarely … the utility of acute pain and
itch, these sensations ruin one's … prolonged pain or itch can result in changes in neural circuitry …

… In this review, we summarize the progress in elucidating the neural circuit mechanism of itch
… brain structures and neural networks could be recruited by both itch and pain, population …

… itch-selective molecules and neurons. However, we know very little about the brain circuits
underlying itch … Thus, our studies reveal a central neural circuit that is critical for itch signal …

… cause pain or itch evoked by innocuous mechanical stimuli, a hallmark symptom for many
chronic pain or itch … The specificity hypothesis suggests the existence of specific neural circuits …

… neuronal circuits responsible for these modalities. Recently, more scientists have begun to
appreciate that many pain- and touch-sensing neurons and circuits are also responsible for …

… GRP + interneurons in laminae I–II are also implicated in itch transmission, although the
nature of the GRP–GRPR neuron circuit is still the subject of much debate. GRP-expressing …

… processing of pain has some similarities to that of itch [11-14]. In addition, neuro… neural
circuits of pain and itch processing in ACC, and the glutaminergic and opioidergic circuits …

… Neural circuits underlying different components of itch. VB thalamus, Po, and S1 (cyan) are
involved in the processing of the sensory component of itch. PBN, … itch and pain modulation. …

… It is still unclear how the neuronal circuits manage to separate out the itch signal when it is
at least partly generated by those fibers which would normally suppress the itch sensation (ie …

… Ca 2+ imaging, activity-dependent labeling with targeted recombination in active populations
(TRAP), optogenetic/chemogenetic manipulations, and virus-mediated circuit tracing, we …