[HTML][HTML] Significant determinants of mouse pain behaviour
MS Minett, N Eijkelkamp, JN Wood - PloS one, 2014 - journals.plos.org
… for conflicting data on the pain phenotypes of knockout mice to be generated by … mouse
pain behaviour that are often overlooked, which may help explain discrepancies in the pain …
pain behaviour that are often overlooked, which may help explain discrepancies in the pain …
Measuring pain in the (knockout) mouse: big challenges in a small mammal
SG Wilson, JS Mogil - Behavioural brain research, 2001 - Elsevier
… in the production and characterization of knockout mice and other defined mutants should
contribute vastly to our understanding of biology in general, and pain research in particular. At …
contribute vastly to our understanding of biology in general, and pain research in particular. At …
Usefulness of knockout mice to clarify the role of the opioid system in chronic pain
R Maldonado, JE Baños… - British journal of …, 2018 - Wiley Online Library
… chronic pain. Behavioural data obtained in these chronic pain models are discussed …
the peculiarities of the behavioural phenotype of each line of knockout mice. These studies …
the peculiarities of the behavioural phenotype of each line of knockout mice. These studies …
Sensory neuronal phenotype in galanin receptor 2 knockout mice: focus on dorsal root ganglion neurone development and pain behaviour
TJS Shi, X Hua, X Lu, S Malkmus… - European Journal of …, 2006 - Wiley Online Library
… hyperalgesia (Kerr et al., 2001), whereas in the GalR2–/– mice (loss distributed over all
size categories of DRG NPs) we could only see minor effects in the pain behavioural tests. …
size categories of DRG NPs) we could only see minor effects in the pain behavioural tests. …
Reduced inflammatory and neuropathic pain and decreased spinal microglial response in fractalkine receptor (CX3CR1) knockout mice
AA Staniland, AK Clark, R Wodarski… - Journal of …, 2010 - Wiley Online Library
… CX3CR1 knockout (KO) mice to examine pain behaviour in the absence of FKN signalling.
Naive CX3CR1 KO mice had normal responses to acute noxious stimuli. However, KO mice …
Naive CX3CR1 KO mice had normal responses to acute noxious stimuli. However, KO mice …
Neuropathic pain is enhanced in δ‐opioid receptor knockout mice
X Nadal, JE Baños, BL Kieffer… - European Journal of …, 2006 - Wiley Online Library
… pain in DOR knockout mice and wild-type littermates. The behavioural manifestations of
neuropathic pain … The behavioural responses were determined under basal conditions and 3 (D3…
neuropathic pain … The behavioural responses were determined under basal conditions and 3 (D3…
Development and expression of neuropathic pain in CB1 knockout mice
A Castañé, E Célérier, M Martín, C Ledent… - …, 2006 - Elsevier
… the behavioural manifestations of neuropathic pain in both WT and CB1 KO mice exposed
… Our results reveal that CB1 cannabinoid receptor knockout mice do not show altered pain …
… Our results reveal that CB1 cannabinoid receptor knockout mice do not show altered pain …
Exploring the role of nociceptor-specific sodium channels in pain transmission using Nav1. 8 and Nav1. 9 knockout mice
S Leo, R D'Hooge, T Meert - Behavioural brain research, 2010 - Elsevier
… channels in different pain states. Using Na v 1.8 and Na v 1.9 knockout mice, we found …
play a role in cold allodynia in neuropathic pain conditions. Moreover, genetic deletion of Na v …
play a role in cold allodynia in neuropathic pain conditions. Moreover, genetic deletion of Na v …
Opioids: first lessons from knockout mice
BL Kieffer, BL Kieffer - Trends in pharmacological sciences, 1999 - cell.com
… to pain, stress and emotions when activated by endogenous opioid peptides. Recently, mice
… Observations on mutant mice have shed new light on the mode of action of opioids, opioid …
… Observations on mutant mice have shed new light on the mode of action of opioids, opioid …
Inflammatory pain is enhanced in delta opioid receptor‐knockout mice
C Gavériaux‐Ruff, LA Karchewski… - European Journal of …, 2008 - Wiley Online Library
… delta receptors inhibit inflammatory pain when activated either … pain in delta‐receptor
knockout mice. The delta receptor definitely represents a promising target for treating chronic pain …
knockout mice. The delta receptor definitely represents a promising target for treating chronic pain …
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