Evidence for pain modulation by pre-and postsynaptic noradrenergic receptors in the medulla oblongata

J Sagen, HK Proudfit - Brain research, 1985 - Elsevier
… on the midline of the medulla oblongata modulates pain perception. Activation of neurons in
… This action probably results from inhibition of spinal cord pain transmission pathways since …

The medulla oblongata: The vital center for descending modulation

K Ren - The Journal of Pain, 2002 - jpain.org
… The medulla oblongata is classically termed the vital center for life with its critical … It is not
surprising that the structures that are vital for pain modulation are also located in the medulla to …

[HTML][HTML] The caudal ventrolateral medulla as an important inhibitory modulator of pain transmission in the spinal cord

I Tavares, D Lima - The Journal of Pain, 2002 - Elsevier
modulation from the medulla oblongata with the exception of the RVM. Another characteristic
of pain modulation from the medulla oblongata is … which facilitation of pain transmission, ie, …

Neurons in the caudal ventrolateral medulla mediate descending pain control

X Gu, YZ Zhang, JJ O'Malley, CC De Preter… - Nature …, 2023 - nature.com
… The medulla oblongata has previously been implicated in this type of pain control, but the
neurons and … effects, where modulation of pain likely has an adaptive advantage. For example, …

Pain modulation from the brain during diabetic neuropathy: uncovering the role of the rostroventromedial medulla

M Silva, JT Costa-Pereira, D Martins, I Tavares - Neurobiology of disease, 2016 - Elsevier
medulla (RVM) in descending pain modulation, this review will mainly focus in this key area
of the pain … , which affects the brain area where the RVM is located (the medulla oblongata). …

Nucleus cuneiformis and pain modulation: anatomy and behavioral pharmacology

FP Zemlan, MM Behbehani - Brain research, 1988 - Elsevier
… 8 Chung, JM, Kevetter, GA, Yezierski, RP, Haber, LE, Martin, RF and Willis, WD, Midbrain
nuclei projecting to the medial medulla oblongata in the monkey, J. Comp. Neurol., 214 (1983) …

Neurochemical changes in the rostral ventromedial nucleus of the medulla oblongata in rats with developing neuropathic pain

IV Manzhulo, IV Dyuizen - Neurochemical Journal, 2015 - Springer
… that in neuropathic pain the increased agma tine degradation that has been observed in the
neurons of the important bulbar center of endogenous pain modulation is direct evidence of …

… of spinal cord neurones during hypertension involves the spinal GABAergic system and a pain modulatory center located at the caudal ventrolateral medulla

M Morato, D Pinho, T Sousa, I Tavares… - Journal of …, 2006 - Wiley Online Library
… The VLMlat was further shown to be the VLM area responsible for pain modulation (Tavares …
After perfusion, the medulla oblongata and spinal segment L 2 were post-fixated and …

Cortical and subcortical modulation of pain

MD Felice, MH Ossipov - Pain management, 2016 - Taylor & Francis
pain modulation arising from the periaqueductal gray (PAG) and activating the rostral
ventromedial medulla (… From the linear system of pain modulation through the PAG–RVM system, …

The 'in's and out's' of descending pain modulation from the rostral ventromedial medulla

CC De Preter, MM Heinricher - Trends in Neurosciences, 2024 - cell.com
… -pain modulating circuit controls the experience of pain by … This circuit’s key output node,
the rostral ventromedial medulla … respectively suppress or facilitate pain-related sensory pro…