… capsaicin receptor by using a Ca2+ imaging—based expression strategy (5). The cloned
capsaicin receptor was designated vanilloid receptor … component of both capsaicin and its ultra …

… We reasoned that a capsaicin receptor-encoding cDNA might … capsaicin, assuming that
capsaicin acts at a proteinaceous site and that a single cDNA can confer sensitivity to capsaicin …

… These properties of capsaicin may explain its efficacy in treating some painful … capsaicin-like
molecule that promotes pain and inflammation by interacting with the capsaicin receptor…

… To assess pain-related behavior, we injected capsaicin or resiniferatoxin into the plantar
skin of the hind paw (35). In wild-type mice, this stimulus elicited a robust licking and shaking of …

… The capsaicin receptor, named transient receptor potential vanilloid 1 … in pharmacological
responses between TRPV1 and native capsaicin receptors for the presence of regulatory …

… to shed light upon capsaicin working both as a tool to understand pain but also as a treatment
for chronic pain. This review will discuss the various actions of capsaicin and how it lends …

… identifying the capsaicin receptor was to determinewhether known pain-producing stimuli
might exert their effects by acting atthis same site. With a functional vanilloid receptor cDNA in …

… The capsaicin receptor TRPV1 is normally activated with a threshold that corresponds to
the onset of tissue damage and pain (∼43C) (6). Our studies suggest that this physiologically …

… molecular target of capsaicin, the … capsaicin receptor (VR1) also can be activated by noxious
heat (with a thermal threshold of >43C) or protons (acidification), both of which cause pain …

… response to capsaicin. The heteromeric structure of the capsaicin receptor is particularly
interesting … This assumption is supported by our previous finding that native capsaicin receptors …