Ischemia-reperfusion injuries assessment during pancreas preservation

T Prudhomme, JF Mulvey, LAJ Young… - International Journal of …, 2021 - mdpi.com
… This is of particular interest during pancreas preservation and transplantation, where we are
… measure beta cell death from a “liquid biopsy” of perfusate during pancreas preservation. …

Pancreatic ischemia/reperfusion injury: impact of different preservation temperatures

R Obermaier, O Drognitz, S Benz, UT Hopt, P Pisarski - Pancreas, 2008 - journals.lww.com
… impact of different ischemiapancreatic ischemia/reperfusion. The investigations were
performed in our standardized model of in situ ischemia/reperfusion on a pedunculated pancreatic

Organ preservation in pancreas and islet transplantation

RM Baertschiger, T Berney, P Morel - Current opinion in organ …, 2008 - journals.lww.com
… All these factors are important for pancreas and islet transplantation. A major question in …
published on pancreas preservation, differences between the various preservation solutions …

Pancreas preservation for pancreas and islet transplantation: a minireview

JP Squifflet, H LeDinh, A de Roover… - Transplantation …, 2011 - Elsevier
pancreas graft quality while preventing ischemic reperfusion damages. Oxygenation by 1-
or 2-layer methods during pancreas preservation, as … in pancreas preservation for pancreas

Mechanisms of islet damage mediated by pancreas cold ischemia/rewarming

K Omori, E Kobayashi, J Rawson, M Takahashi… - Cryobiology, 2016 - Elsevier
… involved in pancreas cold ischemia/… preserved rat pancreas preparation, we attempted to
clarify possible mechanisms of islet death associated with prolonged pancreas cold ischemia

[HTML][HTML] Effects of organ preservation, ischemia time and caspase inhibition on apoptosis and microcirculation in rat pancreas transplantation

O Drognitz, R Obermaier, X Liu, H Neeff… - American Journal of …, 2004 - Elsevier
preservation in saline solution resulted in an increase in cell necrosis, indicating a more severe
ischemiareperfusion injury of the pancreatic … that prolongation of preservation time was …

Ischemia and reperfusion in pancreas

TF Hoffmann, R Leiderer, AG Harris… - Microscopy research …, 1997 - Wiley Online Library
… on rat pancreas after induction of pancreatitis by … ischemia/reperfusion of the pancreas in
rats using in vivo fluorescence microscopy. In this model, the 4 arteries supplying the pancreas (…

Preserving and perfusing the allograft pancreas: past, present, and future

S Dholakia, E Royston, EJ Sharples, V Sankaran… - Transplantation …, 2018 - Elsevier
… These results, along with the complexities associated with machine perfusion of the pancreas
have made SCS the preferred and most widely used method for pancreas preservation for …

Beneficial effects of ischemic preconditioning on pancreas cold preservation

AR Hogan, M Doni, RD Molano… - Cell …, 2012 - journals.sagepub.com
ischemia followed by reperfusion prior to extended ischemicpancreatic tissue injury following
cold ischemic preservation. … of warm ischemia followed by 10 min of reperfusion) prior to ~…

THE INFLUENCE OF PANCREAS PRESERVATION ON HUMAN ISLET ISOLATION OUTCOMES: IMPACT OF THE TWO-LAYER METHOD

T Tsujimura, Y Kuroda, J Avila, T Kin… - …, 2004 - journals.lww.com
Aims: Human pancreas preservation for islet transplantation holds additional challenges and
considerations compared to whole pancreas transplantation. The purpose of this study was …