Protective effects of hypothermic ex vivo perfusion on ischemia/reperfusion injury and transplant outcomes

SD Henry, JV Guarrera - Transplantation reviews, 2012 - Elsevier
… Further preclinical investigations of pancreas HMP are warranted. Modifications of HMP …
possible benefits of HMP for pancreas preservation for islet and whole-organ transplantation. …

Characterization of Ischemia/Reperfusion–Induced Gene Expression in Experimental Pancreas Transplantation

O Drognitz, P Michel, D Koczan, H Neeff… - …, 2006 - journals.lww.com
… expressed in the early period after pancreatic cold ischemia/reperfusion (I/R) injury. …
patterns of pancreatic grafts in response to cold ischemia and subsequent reperfusion injury. …

Current state of pancreas preservation and implications for DCD pancreas transplantation

AD Barlow, SA Hosgood, ML Nicholson - Transplantation, 2013 - journals.lww.com
preservation techniques for DCD kidneys, improving the outcome of these marginal grafts.
However, the use of such techniques for pancreas preservation … of pancreas preservation for …

The effect of different solutions for organ preservation on immediate postischemic pancreatic function in vitro

U Leonhardt, A Tytko, B Exner, M Barthel… - …, 1993 - journals.lww.com
pancreas preservation (15), the present study compares the effect of UW, HTK, and EC on
parameters verifying several components of ischemic … organ quality after preservation with EC (…

[HTML][HTML] Preservation of pancreas in the University of Wisconsin solution supplemented with AP39 reduces reactive oxygen species production and improves islet graft …

K Nishime, C Miyagi-Shiohira, K Kuwae… - American Journal of …, 2021 - Elsevier
… The islets isolated from the pancreas preserved in UW + AP39 exhibited significantly … isolated
from the pancreas preserved in the vehicle. We found that the pancreas preserved in UW + …

Characterization and reduction of ischemia/reperfusion injury after experimental pancreas transplantation

H Mayer, J Schmidt, J Tbies, E Ryschich… - Journal of …, 1999 - Springer
… transplantation sa cause of early graft pancreatitis. The aim of this study was to quantify
pancreatic microcirculation after pancreas transplantation in correlation with cold ischemia time. …

Preservation of the donor pancreas for whole pancreas and islet transplantation

D Ridgway, D Manas, J Shaw… - Clinical transplantation, 2010 - Wiley Online Library
preservation of a high quality donor pancreaspreservation are practiced to ensure optimal
graft quality. Moreover expanded criteria donors and novel methods of pancreas preservation

Diazoxide, a KATP Channel Opener, Prevents IschemiaReperfusion Injury in Rodent Pancreatic Islets

Y Wang, S Wang, T Harvat, K Kinzer… - Cell …, 2015 - journals.sagepub.com
… of ischemic-induced calcium overload via sarcK ATP channel opening and resting β-cell
membrane potential could prevent insulin granule dumping during pancreas preservation and …

[HTML][HTML] Current trends in organ preservation solutions for pancreas transplantation: a single-center retrospective study

J Ferrer-Fàbrega, E Folch-Puy… - Transplant …, 2022 - frontierspartnerships.org
… the pancreas to ischemia-reperfusion injury, choices regarding preservation solution markedly
affect pancreas … A retrospective single-center analysis of 380 pancreas transplants (2000–…

Exocrine, but not endocrine, tissue is susceptible to microvascular ischemia/reperfusion injury following pancreas transplantation in the rat

B Vollmar, J Janata, J Yamauchi, B Wolf… - Transplant …, 1999 - Wiley Online Library
… Our results also indicate a higher susceptibility of the exocrine pancreas to cold ischemia-reperfusion
events that is associated with significant alterations in nutritive perfusion and, thus, …