[HTML][HTML] Ischemia-reperfusion injuries assessment during pancreas preservation

T Prudhomme, JF Mulvey, LAJ Young… - International Journal of …, 2021 - mdpi.com
… machine perfusion for whole organ pancreas preservation. This review highlights the
ischemia-reperfusion injuries assessment during ex vivo pancreas perfusion, both for assessment …

Pancreatic ischemia/reperfusion injury: impact of different preservation temperatures

R Obermaier, O Drognitz, S Benz, UT Hopt, P Pisarski - Pancreas, 2008 - journals.lww.com
… ) during ischemia, showing reduced mucosal injury and improved … during ischemia is protective
in following ischemia/reperfusion. … ischemia is able to reduce ischemia reperfusion injury. …

Protective effects of hypothermic ex vivo perfusion on ischemia/reperfusion injury and transplant outcomes

SD Henry, JV Guarrera - Transplantation reviews, 2012 - Elsevier
… Modifications of HMP technique, such as nonpulsatile and low-pressure perfusion, may
hold promise in uncovering possible benefits of HMP for pancreas preservation for islet and …

Mechanisms of islet damage mediated by pancreas cold ischemia/rewarming

K Omori, E Kobayashi, J Rawson, M Takahashi… - Cryobiology, 2016 - Elsevier
… in pancreas cold ischemia/rewarming mediated islet damage … Using an en bloc cold
preserved rat pancreas preparation, … pancreas cold ischemia and subsequent rewarming. Cold …

Characterization and reduction of ischemia/reperfusion injury after experimental pancreas transplantation

H Mayer, J Schmidt, J Tbies, E Ryschich… - Journal of …, 1999 - Springer
… microcirculatory injury under standard UW preservation as … shown to limit ischemia/reperfusion
injury in experimental liver … equally effective in pancreas transplantation showing the …

Exocrine, but not endocrine, tissue is susceptible to microvascular ischemia/reperfusion injury following pancreas transplantation in the rat

B Vollmar, J Janata, J Yamauchi, B Wolf… - Transplant …, 1999 - Wiley Online Library
… of pancreatic endocrine tissue was preserved without any significant change in the incidence
of intermittent capillary perfusion. Thus, our results indicate a higher susceptibility of the …

Organ preservation in pancreas and islet transplantation

RM Baertschiger, T Berney, P Morel - Current opinion in organ …, 2008 - journals.lww.com
… Organ preservation aims at reducing ischemiareperfusion injury and maintains or even
improves its function, and, therefore, increases transplant safety and efficiency. With the chronic …

Ischemia and reperfusion in pancreas

TF Hoffmann, R Leiderer, AG Harris… - Microscopy research …, 1997 - Wiley Online Library
… postischemic reperfusion injury of the pancreas. In the following, we describe the pathophysiology
of ischemia/reperfusion injury with special reference to the pancreatic microcirculation …

[HTML][HTML] Effects of organ preservation, ischemia time and caspase inhibition on apoptosis and microcirculation in rat pancreas transplantation

O Drognitz, R Obermaier, X Liu, H Neeff… - American Journal of …, 2004 - Elsevier
… Our results suggest that caspase inhibition is capable to attenuate pancreatic cold
ischemiareperfusion injury by a significant decrease of apoptotic cell death. However, as the …

A novel technique for heterotopic vascularized pancreas transplantation in mice to assess ischemia reperfusion injury and graft pancreatitis

M Maglione, M Hermann, P Hengster, S Schneeberger… - Surgery, 2007 - Elsevier
… as well as novel therapeutic strategies of preservation, ischemia reperfusion injury, and
graft pancreatitis. Simultaneous kidney-pancreas transplantation is currently the treatment of …