Impact of two-layer pancreas preservation on islet isolation and transplantation1

BJ Hering, I Matsumoto, T Sawada, M Nakano… - …, 2002 - journals.lww.com
… , the functional success rate with two-layer and standard UW preservation was 56%. …
pancreas preservation techniques before islet isolation in a Lewis rat–to–diabetic nude mouse islet

THE INFLUENCE OF PANCREAS PRESERVATION ON HUMAN ISLET ISOLATION OUTCOMES: IMPACT OF THE TWO-LAYER METHOD

T Tsujimura, Y Kuroda, J Avila, T Kin… - …, 2004 - journals.lww.com
Aims: Human pancreas preservation for islet transplantation holds additional challenges and
considerations compared to whole pancreas transplantation. The purpose of this study was …

Two-layer method in short-term pancreas preservation for successful islet isolation

P Witkowski, Z Liu, Q Guo, E Poumian-Ruiz… - Transplantation …, 2005 - Elsevier
preserved with UW solution.1, 2 Although after brief cold preservation of pancreas with UW
solution, islet isolation … standard preservation solution for human pancreas recovered for islet

Influence of preservation solution on human islet isolation outcome

T Hubert, V Gmyr, L Arnalsteen, T Jany… - …, 2007 - journals.lww.com
… -free preservation solutions might be suboptimal for pancreas perfusion and cold storage prior
to islet isolation … Because pancreata are now frequently recovered for islet transplantation, …

Pancreas preservation fluid microbial contamination is associated with poor islet isolation outcomes–a multi‐centre cohort study

RPH Meier, DO Andrey, P Sun, N Niclauss… - Transplant …, 2018 - Wiley Online Library
… final islet … , isolation to islet infusion, to ensure clinical safety of the islet transplantation. This
study presents the microbial analysis of islet isolation/transplantation, the impact on isolation

Pancreas preservation by the 2-layer cold storage method before islet isolation protects isolated islets against apoptosis through the mitochondrial pathway

T Matsuda, Y Suzuki, Y Tanioka, H Toyama, K Kakinoki… - Surgery, 2003 - Elsevier
… that rat pancreas preservation by TLM before islet isolation protected isolated islets against
… MAPK pathway, and that JNKs in isolated islets were preferentially activated in response to …

Improvement of pancreatic islet cell isolation for transplantation

S Matsumoto, H Noguchi, B Naziruddin… - Baylor University …, 2007 - Taylor & Francis
… Efficacy of the oxygen-charged static two-layer method for short-term pancreas preservation
and islet isolation from nonhuman primate and human pancreata. Cell Transplant 2002;11(8…

Preservation and storage of pancreatic islets

R Jindal, D Gray - Transplantation, 1994 - journals.lww.com
pancreas for islet isolation and purification, estimation of islet … of isolated islets is inadequate
for transplantation, the islets … the best method of preserving islets, particularly for relatively …

Low-temperature preservation of isolated islets is superior to conventional islet culture before islet transplantation

H Noguchi, B Naziruddin, A Jackson, M Shimoda… - …, 2010 - journals.lww.com
… culture conditions after islet isolation is extremely important for clinical islet transplantation.
… than half of the islets from a given pancreas, necessitating islet transplantation from two or …

Isolation and preservation of islets from the mouse, rat, guinea-pig and human pancreas

J Ferguson, RH Allsopp, RMR Taylor… - Journal of British …, 1976 - academic.oup.com
isolation of pancreatic islets from laboratory rodents and from the human pancreas.
Animal … in a manner similar to islets isolated from cadaver pancreas (Cases 7 and 8, Fig. 3). …