Role of Wnt/β-catenin signaling in drug resistance of pancreatic cancer
J Cui, W Jiang, S Wang, L Wang… - Current pharmaceutical …, 2012 - ingentaconnect.com
… of pancreatic cancer. Conceivably, the dysregulation of Wnt/β-catenin signaling pathway is
involved in pancreatic cancer … Though researchers have proven it in some other cancer types, …
involved in pancreatic cancer … Though researchers have proven it in some other cancer types, …
Therapeutic potential of targeting the Wnt/β‐catenin pathway in the treatment of pancreatic cancer
SA Javadinia, S Shahidsales… - Journal of Cellular …, 2019 - Wiley Online Library
… , including pancreatic … β‐catenin, and activation of target genes leads to a more aggressive
phenotype, suggesting its potential value as a therapeutic target in the treatment of pancreatic …
phenotype, suggesting its potential value as a therapeutic target in the treatment of pancreatic …
[HTML][HTML] β-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice
JP Morris, DA Cano, S Sekine… - The Journal of …, 2010 - Am Soc Clin Investig
… (ADM) and pancreatic cancer precursor lesion formation by blocking acinar regeneration
following acute pancreatitis. Our results indicate that β-catenin is required for efficient acinar …
following acute pancreatitis. Our results indicate that β-catenin is required for efficient acinar …
[HTML][HTML] Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and β-catenin stabilization
L Wang, DG Heidt, CJ Lee, H Yang, CD Logsdon… - Cancer cell, 2009 - cell.com
… of β-catenin. Besides highlighting ATDC as a potential therapeutic target … pancreatic
cancer, our studies have defined a mechanism for activating Wnt/β-catenin signaling in cancer…
cancer, our studies have defined a mechanism for activating Wnt/β-catenin signaling in cancer…
[HTML][HTML] Wnt/β-catenin signaling: the culprit in pancreatic carcinogenesis and therapeutic resistance
… In this review, we have summarized the role of Wnt signaling in pancreatic cancer and
suggested future directions to enhance the survival of pancreatic cancer patients. …
suggested future directions to enhance the survival of pancreatic cancer patients. …
[HTML][HTML] TOP2A induces malignant character of pancreatic cancer through activating β-catenin signaling pathway
Y Pei, X Yin, X Liu - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
… Knockdown of TOP2A in pancreatic cancer cell lines inhibited cell … -catenin pathway in
pancreatic cancer. Mechanistically, we demonstrated TOP2A acts as a co-activator ofβ-catenin …
pancreatic cancer. Mechanistically, we demonstrated TOP2A acts as a co-activator ofβ-catenin …
[HTML][HTML] Differentiation therapy targeting the β-catenin/CBP interaction in pancreatic cancer
P Manegold, KKY Lai, Y Wu, JL Teo, HJ Lenz… - Cancers, 2018 - mdpi.com
… in human pancreatic cancer cells and in … /β-catenin interaction in pancreatic cancer; and
that ICG-001 specific antagonism of the CBP/β-catenin interaction sensitizes pancreatic cancer …
that ICG-001 specific antagonism of the CBP/β-catenin interaction sensitizes pancreatic cancer …
[HTML][HTML] β-Catenin expression is associated with cell invasiveness in pancreatic cancer
JN Nan, OR Kim, MA Lee - The Korean journal of internal medicine, 2019 - ncbi.nlm.nih.gov
… the role of β-catenin in invasion in pancreatic cancer. … As reported in previous studies, the
Wnt/β-catenin pathway can … Wnt/β-catenin signaling pathway by using pancreatic cancer cell …
Wnt/β-catenin pathway can … Wnt/β-catenin signaling pathway by using pancreatic cancer cell …
[HTML][HTML] β-catenin up-regulates the expression of cyclinD1, c-myc and MMP-7 in human pancreatic cancer: relationships with carcinogenesis and metastasis
YJ Li, ZM Wei, YX Meng, XR Ji - World journal of gastroenterology …, 2005 - ncbi.nlm.nih.gov
… in pancreatic cancer, and the results were conflicting[7,23-28]. … of pancreatic cancer, we
detected expression of β-catenin, cyclinD1, c-myc and MMP-7 in normal pancreas, pancreatic …
detected expression of β-catenin, cyclinD1, c-myc and MMP-7 in normal pancreas, pancreatic …
Inflammation promotes progression of pancreatic cancer through WNT/β-catenin pathway-dependent manner
R Ren, J Yu, Y Zhang, SF Wang, X Guo, M Shen… - Pancreas, 2019 - journals.lww.com
… in the pancreatic cancer progression is still far from defined. … of pancreatic tumor immune
escape, identified WNT/β-catenin … process of inflammation carcinogenesis in pancreatic cancer. …
escape, identified WNT/β-catenin … process of inflammation carcinogenesis in pancreatic cancer. …
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