过去一年中添加的文章,按日期排序

Bufadienolide-Fatty Acid Conjugates from the Fertilized Eggs of Toad Bufo gargarizans: Isolation, Characterization, Toxicity, and Antiproliferative Evaluation

Z Chen, Q Yu, J Chen, X Yu, J Cao, Y Zhai… - Journal of Agricultural …, 2024 - ACS Publications
6 天前 - … for their antiproliferative activities in pancreatic cancer cell lines ASPC-1 and …
PI3K/Akt/mTOR pathway in PANC10.05. Moreover, we assessed the efficacy of 6 and 7 on cancer

[PDF][PDF] Investigating underlying molecular mechanisms, signaling pathways, emerging therapeutic approaches in pancreatic cancer

M Mustafa, K Abbas, M Alam, S Habib, GMH Zulfareen… - 2024 - researchgate.net
11 天前 - … In pancreatic cancer, the PI3K/AKT/mTOR pathway … subunit of PI3K; damage to
the function of the tumor suppressor … Furthermore, the PI3K/AKT/mTOR pathway engages in …

Therapeutic mechanism of aqueous extract of Semiliquidambar cathayensis Chang root for pancreatic cancer: the active components, therapeutic targets and …

Y Huang, L Qin, S Guan, Y Guang… - Nan fang yi ke da …, 2024 - pubmed.ncbi.nlm.nih.gov
11 天前 - … of PI3K and AKT in Panc-1 cells (P < 0.001). Conclusion: The therapeutic effect of
SC root against pancreatic cancer … targets and pathways including the PI3K-Akt pathway. …

Flubendazole presents anti-tumor effects by promoting cell cycle arrest and inhibiting the invadopodia in pancreatic cancer

P Zhao, Z Wang, X Huang, K Xue, X Liu, B Tian - 2024 - researchsquare.com
14 天前 - … the PI3K-Akt pathway and found that both PI3K and 275 … PI3K in invadopodia46.
In our study, flubendazole 383 decreased the PI3K and phosphorylated Akt, while the total Akt

Soluble T-cadherin secretion from endothelial cells is regulated via Insulin/PI3K/Akt signalling.

T Okita, S Kita, S Fukuda, Y Kondo, T Sakaue… - Biochemical and …, 2024 - Elsevier
17 天前 - Aim and objective Our recent report showed that soluble T-cadherin promotes
pancreatic beta-cell proliferation. However, how and where the secretion of soluble T-cadherin is …

Development of Novel Therapy Targeting Autophagy Against Advanced and Chemo-resistant Pancreatic Cancer.

JE Gillson - 2024 - ses.library.usyd.edu.au
20 天前 - … dysregulation to the MAPK and PI3K/AKT pathways and a hyperactivated
metabolism when compared to the parent cells. These networks are all linked through AMPK, …

Mechanisms of resistance to oncogenic KRAS inhibition in pancreatic cancer

J Dilly, MT Hoffman, L Abbassi, Z Li, F Paradiso… - Cancer …, 2024 - aacrjournals.org
23 天前 - … In PDAC cell lines and organoid models treated with the KRASG12D inhibitor
MRTX1133, epithelial-to-mesenchymal transition and PI3K-AKT-mTOR signaling associate with …

[HTML][HTML] Progress on the effects and underlying mechanisms of evodiamine in digestive system diseases, and its toxicity: A systematic review and meta-analysis.

Z Zhou, Y Zhou, Z Zhang, M Zhao, C Hu, L Yang… - Phytomedicine, 2024 - Elsevier
25 天前 - … on pancreatic cancer, radiation enteritis, gastric cancer, tongue squamous cancer,
hepatitis B, oral cancer, and esophageal cancer … The PI3K-AKT signaling pathway could be …

Recent advances on cyanidin-3-O-glucoside in preventing obesity-related metabolic disorders: A comprehensive review

OD Zad, S Al-Dalali, L Zhao, L Zhao, C Wang - … and Biophysical Research …, 2024 - Elsevier
28 天前 - … pathway activation, promoting autophagy, protecting pancreatic β-cells from oxidative
stress … -1 and GLUT-4 expression and regulating the PI3K/Akt pathway. C3G exhibits anti-…

Synthesis and Biological Activity of 2-Chloro-8-methoxy-5-methyl-5H-indolo [2,3-b] Quinoline for the Treatment of Colorectal Cancer by Modulating PI3K/AKT/mTOR …

Y Ma, H Zhu, X Jiang, Z Zhou, Y Zhou, Y Tian, L Tu… - ACS …, 2024 - ACS Publications
29 天前 - … and its cytotoxicity was assessed on pancreatic cancer PANC-1 cells, colorectal
cancer HCT116 cells, liver cancer SMMC-7721 cells, and gastric cancer AGS cells in vitro. The …