Effects of evodiamine on PI3K/Akt and MAPK/ERK signaling pathways in pancreatic cancer cells
Z Hong, Z Wang, B Zhou, J Wang… - International …, 2020 - spandidos-publications.com
… the proliferation, apoptosis and autophagy of human pancreatic cancer (PC) cell lines in vitro
… to establish an orthotopic pancreatic tumor model in nude mice. Tumor‑bearing nude mice …
… to establish an orthotopic pancreatic tumor model in nude mice. Tumor‑bearing nude mice …
α‐Mangostin suppresses the viability and epithelial‐mesenchymal transition of pancreatic cancer cells by downregulating the PI3K/Akt pathway
Q Xu, J Ma, J Lei, W Duan, L Sheng… - BioMed research …, 2014 - Wiley Online Library
… of the PI3K/Akt pathway in pancreatic cancer cells as demonstrated by the reduction of the
Akt … Finally, α-mangostin significantly inhibited the growth of BxPc-3 tumor mouse xenografts. …
Akt … Finally, α-mangostin significantly inhibited the growth of BxPc-3 tumor mouse xenografts. …
Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway
Z Zhao, C Li, H Xi, Y Gao, D Xu - Molecular medicine …, 2015 - spandidos-publications.com
… ‑9/3 activation in the pancreatic cancer cells. Using siRNA against FOXO1, and Akt inhibitor
and … by inhibition of phosphoinositide 3‑kinase/Akt signaling, leading to cell cycle arrest and …
and … by inhibition of phosphoinositide 3‑kinase/Akt signaling, leading to cell cycle arrest and …
Mitofusin2 induces cell autophagy of pancreatic cancer through inhibiting the PI3K/Akt/mTOR signaling pathway
R Xue, Q Meng, D Lu, X Liu, Y Wang… - Oxidative Medicine and …, 2018 - Wiley Online Library
… pancreatic cancer cell autophagy by inhibiting the PI3K/AKT/… PI3K/Akt/mTOR signaling
pathway in pancreatic cancer. The autophagy declines the ROS production of pancreatic cancer. …
pathway in pancreatic cancer. The autophagy declines the ROS production of pancreatic cancer. …
Curcumin inhibits superoxide dismutase-induced epithelial-to-mesenchymal transition via the PI3K/Akt/NF-κB pathway in pancreatic cancer cells
W Li, Z Jiang, X Xiao, Z Wang… - … journal of oncology, 2018 - spandidos-publications.com
… 24 h reduced the migration of pancreatic cancer cells without the addition of SOD (… pancreatic
cancer through suppression of the PI3K/Akt/NF-κB signaling pathway in pancreatic cancer …
cancer through suppression of the PI3K/Akt/NF-κB signaling pathway in pancreatic cancer …
Girdin regulates the proliferation and apoptosis of pancreatic cancer cells via the PI3K/Akt signalling pathway
S Wang, Y Lei, Z Cai, X Ye, L Li… - Oncology …, 2018 - spandidos-publications.com
… may influence pancreatic cancer cell processes via the PI3K/Akt pathway. … PI3K/Akt pathway
by western blotting. Following rAd-shGirdin infection, levels of p-PI3K (Thy 508) and p-Akt (…
by western blotting. Following rAd-shGirdin infection, levels of p-PI3K (Thy 508) and p-Akt (…
CUX1: target of Akt signalling and mediator of resistance to apoptosis in pancreatic cancer
S Ripka, A Neesse, J Riedel, E Bug, A Aigner… - Gut, 2010 - gut.bmj.com
… To examine the relevance of CUX1 as a downstream effector in PI3K/Akt-induced resistance
to apoptosis, we modulated CUX1 expression either directly by siRNA or by inhibiting …
to apoptosis, we modulated CUX1 expression either directly by siRNA or by inhibiting …
Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells
… via inhibition of PI3K/Akt/mTOR pathway … pancreatic cancer contains pancreatic CSCs, we
sought to examine the molecular mechanism by which ROT induces autophagy in pancreatic …
sought to examine the molecular mechanism by which ROT induces autophagy in pancreatic …
Pancreatic stellate cells derived exosomal miR-5703 promotes pancreatic cancer by downregulating CMTM4 and activating PI3K/Akt pathway
M Li, H Guo, Q Wang, K Chen, K Marko, X Tian, Y Yang - Cancer Letters, 2020 - Elsevier
… , and could activate PI3K/Akt pathway by interacting with the SH3 domain of PI3K regulatory
… PAK4 and PI3K/Akt pathway. Western blot analysis showed that the levels of PAK4, p-Akt, p-…
… PAK4 and PI3K/Akt pathway. Western blot analysis showed that the levels of PAK4, p-Akt, p-…
Inhibition of Notch3 enhances sensitivity to gemcitabine in pancreatic cancer through an inactivation of PI3K/Akt-dependent pathway
J Yao, C Qian - Medical Oncology, 2010 - Springer
… In this study, we tested the hypothesis that Akt is a key downstream target by … pancreatic
cancer cells and that suppression of Notch3/PI3K/Akt pathway would enhance pancreatic cancer …
cancer cells and that suppression of Notch3/PI3K/Akt pathway would enhance pancreatic cancer …