… -targeting inhibitors as effective strategies to overcome PI3K/AKT-dependent … -deficient
pancreatic cancer cells is PI3K/AKT dependent, and down-regulated phosphorylation of AKT by …

… Carboxypeptidase A4 (CPA4), as a novel tumor biomarker, is prevalently observed in various
cancers. However, the potential role of CPA4 in pancreatic cancer (PC), to our knowledge, …

… of PI3K/AKT/GSK signalling. The present study demonstrated NGF/TrkA promoted the PC
cell proliferation and invasion in the co-culture system by the activation of the PI3K/AKT/GSK …

… in pancreatic cancer by activating the PI3K/AKT signaling … the invasion and metastasis of
pancreatic cancer cells [16], [17], … pancreatic cancer via upregulating VEGF through PI3K-AKT …

… (HBx) on proliferation and migration of the pancreatic cancer cell lines PANC-1 and SW1990…
including PI3K/AKT, MAPK, and ERK were upregulated. Inhibition of the PI3K/AKT pathway …

… the tumor suppressive ability of STK3 in vivo. Collectively, this study found that STK3
regulates pancreatic cancer cell proliferation and apoptosis by suppressing the PI3K/AKT/mTOR …

… TMEM158 activates PI3K/AKT signaling pathway in PC cells. (a) Expression profile of
phosphorylated PI3K and AKT, total PI3K and AKT in TMEM158 knockdown or overexpression PC …

… the PI3K/AKT pathway: PI3K, PDK1, c-Raf and PTEN. Moreover, pretreatment with the
PI3K/AKT-… in an AKT-dependent manner. Consistently, ectopic expression of constitutively active …

… Erlotinib/Ginsenoside Rg3 treatment decreased the levels of p-EGFR, p-PI3K, and p-Akt …
pancreatic cancer cells via induction of apoptosis and downregulation of the EGFR/PI3K/AKT …

… the levels of p-AKT, AKT, p-PI3K and PI3K in pancreatic cancer cells. As displayed in …
AKT/AKT and p-PI3K/PI3K were both reduced than that in si-NC group in the two pancreatic cancer …