… in pancreatic cancer cells. Our results demonstrate that Par-4 downregulation confers CDDP
resistance in pancreatic cancer cells probably via induction of PI3K/Akt … in pancreatic cancer …

… in pancreatic cancer. Therefore, we aimed to investigate the effect of miR-873 … pancreatic
cancer and its possible interaction with PLEK2 and the PI3K/AKT pathway in pancreatic cancer. …

… for assessing PI3K–AKT pathway activation, the present study demonstrated that NOS–PI3K–AKT
signaling also mediates cell invasion. Two closely related members of the AKT/PKB …

… study suggested that LE induced apoptosis of pancreatic cancer cells via ROS generation
to modulate the p38 and PI3K/AKT pathways and could be a promising anti-pancreatic agent. …

… regulatory effect of POTEE on the PI3K/Akt/GSK-3β/β-catenin pathway in pancreatic cancer.
Our findings may provide a novel idea in the screening and treatment of pancreatic cancer. …

… of PI3K/Akt signaling would compromise the full potential of MEK inhibitors to sensitize pancreatic
cancer cells … the response of a panel of pancreatic tumor models to MEK inhibition with …

… of lucidone and GEM suppressed pancreatic cancer cell proliferation by reducing
autophagy and facilitating apoptosis through the HMGB1/RAGE/PI3K/Akt signaling pathway. …

… -pancreatic cancer activity of the corn silk polysaccharide has not been reported to date. In
this study, the anti-pancreatic cancer … against the EGFR/PI3K/AKT/CREB signaling pathway …

… of human pancreatic cancer cells to GEM. In this study, therefore, whether MET can regulate
the PI3K/Akt/mTOR signaling pathway and enhance the sensitivity of human pancreatic can…

… We conclude that the impact of suppressing feedback loops mediated by the PI3K/AKT/mTOR
pathway depends on cell context and leads to different MEK/ERK outcomes in …