… all PDAC, this cancer type is arguably the most RAS-addicted cancer. With substantial …
Cancer Institute identified targeting KRAS as one of four major priorities for pancreatic cancer …

… high expression of TP63 and its target genes as key features in adenosquamous pancreatic
tumours. Furthermore, hypermethylation and down-regulation of genes involved in the …

… Other EGFR and HER2 targeted therapies, including the antibodies cetuximab and …
benefit in patients with pancreatic cancer, as was also true for targeting of vascular endothelial …

… and motility of pancreatic cancer cell, future … targeted therapy with current anti pancreatic
cancer drugs. CTHRC1 appears as a promising target in sequestering pancreatic cancer from …

… in pancreatic cancer cells and promotes tumorigenesis and metastasis. … targeting NF-κB
in conjunction with either classical chemotherapy, such as gemcitabine or other targeted …

… These changes contribute to create a state of autophagy dependence, which can be
therapeutically targeted. This concept was further validated in several pancreatic cancer cell lines …

… Our previous study indicated HIF1 as a critical transcriptional factor in pancreatic cancer cell
… of LASP-1 in pancreatic cancer cells, we used specific siRNAs targeting HIF1α to effectively …

… Pancreatic cancer cells induce a desmoplastic response within the tumour stroma by …
desmoplastic reaction is critical in PDAC pathogenesis, which makes therapeutic targeting of ECM …

… importance in targeted drug delivery for pancreatic cancers. … -1, and SU86.86 pancreatic
cancer cell lines. ABCC3 is an … of pancreatic cancer and may be used for cell surface-targeted …

… pancreatic cancer at early stages due to the non-specific presenting symptoms, the inaccessibility
of the pancreas … only curative option for patients with pancreatic cancer, but at present, …