[PDF][PDF] Pancreatic cancer: Advances and challenges

CJ Halbrook, CA Lyssiotis, MP di Magliano, A Maitra - Cell, 2023 - cell.com
… Accordingly, there are multiple avenues macrophage metabolism can be targeted to relieve
immune suppression in pancreatic cancer, and ongoing studies in this area aim to exploit …

[HTML][HTML] Targeting fibrosis: The bridge that connects pancreatitis and pancreatic cancer

C Huang, J Iovanna, P Santofimia-Castaño - International Journal of …, 2021 - mdpi.com
pancreatitis to pancreatic cancer. Thus, the role of fibrosis in the crosstalk between pancreatitis
and pancreatic cancer is critical … of pancreatic fibrosis in inflammation and cancer, and we …

[HTML][HTML] Pancreatic cancer stromal biology and therapy

D Xie, K Xie - Genes & diseases, 2015 - Elsevier
… development and progression has led to the development of potential targeted therapies
for pancreatic cancer, some of which appear to be promising and exhibit synergistic efficacy in …

Target c-Myc to treat pancreatic cancer

M Ala - Cancer biology & therapy, 2022 - Taylor & Francis
… , and pancreatic neuroendocrine tumors. Pancreatic cancer in this review is considered
pancreatic … Herein, in this review, a new target for chemotherapy with pronounced involvement in …

[HTML][HTML] T lymphocytes: a promising immunotherapeutic target for pancreatitis and pancreatic cancer?

Q Zhou, X Tao, S Xia, F Guo, C Pan, H Xiang… - Frontiers in …, 2020 - frontiersin.org
Pancreatic disorders cause a broad spectrum of clinical diseases, mainly including acute and
chronic pancreatitis and pancreatic cancer, … Unfortunately, the pathogenesis of pancreatic

Glycogen synthase kinase-3β: A novel therapeutic target for pancreatic cancer

L Ding, DD Billadeau - Expert opinion on therapeutic targets, 2020 - Taylor & Francis
… of cancer death by 2030 [Citation1–Citation3]. Notably, the absolute number of new cases
and deaths due to pancreatic cancer … and pancreatic cancer accounts for 7.3% of all cancer

The pancreatic cancer genome revisited

A Hayashi, J Hong… - … reviews Gastroenterology & …, 2021 - nature.com
targeted therapies exist — further underscore that pancreatic … information related to pancreatic
cancer genomics with the … a unifying description of the life history of pancreatic cancer. …

[HTML][HTML] Pancreatic cancer: challenges and opportunities

H Zhu, T Li, Y Du, M Li - BMC medicine, 2018 - Springer
… of pancreatic cancer. We briefly introduce the most groundbreaking advances in pancreatic
cancerTargeting ZIP4 might be a novel treatment strategy for PC patients with dysregulated …

Pancreatic cancer: understanding and overcoming chemoresistance

Z Wang, Y Li, A Ahmad, S Banerjee, AS Azmi… - Nature reviews …, 2011 - nature.com
… In summary, targeting cancer stem cells or EMT-phenotype cells by regulating miRNAs could
be a novel strategy for achieving improved treatment outcomes for patients diagnosed with …

[HTML][HTML] Targeting autophagy as a therapeutic strategy against pancreatic cancer

K Yamamoto, D Iwadate, H Kato, Y Nakai… - Journal of …, 2022 - Springer
… tumor growth in various types of cancer, especially those driven by oncogenic mutations
in RAS or RAF, such as lung cancer, pancreatic cancer, and melanoma, where autophagy is …