Pancreatic cancer: optimizing treatment options, new, and emerging targeted therapies

EG Chiorean, AL Coveler - Drug design, development and therapy, 2015 - Taylor & Francis
… to select more patients likely to benefit. Recent reports note activity with immunotherapies
such as CD40 agonists, CCR2 inhibitors, cancer … the heterogeneity within pancreatic cancers. …

[HTML][HTML] Selecting chemotherapy for pancreatic cancer: Far away or so close?

S Shi, X Yu - Seminars in oncology, 2019 - Elsevier
… bias and exact treatment selection process, this study offers … in the therapy of pancreatic
cancer. Although these conclusions … to drive the selection of chemotherapy for pancreatic cancer. …

[HTML][HTML] Selection criteria in resectable pancreatic cancer: a biological and morphological approach

D Tamburrino, S Partelli, S Crippa… - World Journal of …, 2014 - ncbi.nlm.nih.gov
… Focusing on these criteria, we suggest a step-by-step approach for patients with pancreatic
cancer; the first step is to consider their clinical and laboratory factors and then their …

Spotlight on liposomal irinotecan for metastatic pancreatic cancer: patient selection and perspectives

W Woo, ET Carey, M Choi - OncoTargets and therapy, 2019 - Taylor & Francis
… , and further explore the novel approaches to metastatic pancreatic cancer, including nal-IRI.
We will discuss the value of using this drug, associated toxicities, and clinical outcomes. …

[HTML][HTML] Pancreatic cancer biomarkers: A pathway to advance in personalized treatment selection

E Brozos-Vázquez, M Toledano-Fonseca… - Cancer Treatment …, 2024 - Elsevier
… of targeted therapies in pancreatic cancer is … pancreatic cancer. Therefore, this review aims
to offer an updated perspective on biomarkers with therapeutic potential in pancreatic cancer. …

Pharmacogenetics of treatments for pancreatic cancer

B El Hassouni, G Li Petri, DSK Liu… - … opinion on drug …, 2019 - Taylor & Francis
… the pharmacogenetic studies will allow the selection of more effective drugs. However,
the … selected on the basis of standard criteria versus treatment selection based on patient/cancer

An In vivo Platform for Translational Drug Development in Pancreatic Cancer

B Rubio-Viqueira, A Jimeno, G Cusatis, X Zhang… - Clinical cancer …, 2006 - AACR
… expected frequency for pancreatic cancer, suggesting that these carcinomas are representative
of pancreatic cancer as a whole. In contrast, the expression of a selected group of genes …

Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer

E Giovannetti, V Mey, S Nannizzi, G Pasqualetti… - Molecular Cancer …, 2006 - AACR
… the aggressive behavior of pancreatic cancer and influence response … pancreas cancer
chemotherapy relies on the identification of molecular markers that help in the selection of drugs

Therapeutic advances in pancreatic cancer

AS Paulson, HST Cao, MA Tempero, AM Lowy - Gastroenterology, 2013 - Elsevier
drug combinations will be selected based on biomarkers, and strategies for pancreatic cancer
… We review the major advances in pancreatic cancer therapy during the last 5 years, and …

Identifying pancreatic cancer patients for targeted treatment: the challenges and limitations of the current selection process and vision for the future

SL Showalter, S Charles, J Belin… - … opinion on drug …, 2010 - Taylor & Francis
… a selected group of pancreatic cancers deficient in the FANC/BRCA pathway. Theoretically,
this approach would prove to be less systemically toxic than traditional chemotherapy, and at …