Positive selection of gene-modified cells increases the efficacy of pancreatic cancer suicide gene therapy

J Martinez-Quintanilla, M Cascallo, A Gros… - Molecular cancer …, 2009 - AACR
Pancreatic cancer is the fourth leading cause of cancer-… Conventional treatments for pancreatic
cancer are scarcely … Suicide or prodrug-converting cancer gene therapy may represent a …

[HTML][HTML] Targeted therapies for pancreatic cancer

PA Philip - Gastrointestinal cancer research: GCR, 2008 - ncbi.nlm.nih.gov
… patients with pancreatic cancer is extremely … selection in trials of interventions are needed
to improve the yield from research efforts. Pancreatic cancer remains a major cause of cancer

Pancreatic cancer organoids recapitulate disease and allow personalized drug screening

E Driehuis, A Van Hoeck, K Moore… - Proceedings of the …, 2019 - National Acad Sciences
… that specific targeted therapies will be effective in only a subset of patients, and, as such,
a personalized approach will be required to select the right drug for each individual patient. …

Epigenetic treatment of pancreatic cancer: is there a therapeutic perspective on the horizon?

E Hessmann, SA Johnsen, JT Siveke, V Ellenrieder - Gut, 2017 - gut.bmj.com
… Compared with HDACs, the contribution of HATs to pancreatic cancer formation and
progression is multifaceted and highly dependent on the cellular context and the selection of …

[HTML][HTML] Novel strategies for managing pancreatic cancer

WS Loc, JP Smith, G Matters, M Kester… - World journal of …, 2014 - ncbi.nlm.nih.gov
selected genetic markers, and advances in nanomedicine for early diagnosis of pancreatic
cancer… with a family history of pancreatic cancer, chronic pancreatitis, precancerous lesions, …

Chemotherapy regimens for advanced pancreatic cancer: a systematic review and network meta-analysis

GK Gresham, GA Wells, S Gill, C Cameron, DJ Jonker - BMC cancer, 2014 - Springer
… Gemcitabine, an established standard therapy for advanced pancreatic cancer, was
selected as the reference comparator in the Bayesian network meta-analysis because it has …

Selecting the optimal parameters for sonoporation of pancreatic cancer in a pre-clinical model

CW Schultz, G Ruiz de Garibay, A Langer… - Cancer Biology & …, 2021 - Taylor & Francis
… Previously gemcitabine has been dosed at 100 mg/kg publications for pancreatic cancer,
in … at 15 mg/kg for IV injections in pancreatic cancer, Citation42 and when we performed IP …

Prognostic factors in patients with pancreatic cancer

DX Zhang, YD Dai, SX Yuan… - Experimental and …, 2012 - spandidos-publications.com
pancreatic cancer prognosis. Furthermore, there have been no reports of the selection of
pancreatic cancer … , treatment selection and laboratory test data for pancreatic cancer to guide …

Pancreatic cancer: systemic combination therapies for a heterogeneous disease

D Melisi, L Calvetti, M Frizziero… - Current pharmaceutical …, 2014 - ingentaconnect.com
… In this scenario the evaluation of targeted therapies that block inflammatory pathways
activated in the context of anti-angiogenic treatment would be important to select candidate drugs

[HTML][HTML] Adjuvant treatment for pancreatic cancer

U Klaiber, T Hackert… - Translational …, 2019 - ncbi.nlm.nih.gov
… times of 54.4 months in selected patients. Despite improved … new drug targets, and stratification
strategies to better select … adjuvant treatment for pancreatic cancer, identifies evidence …