[HTML][HTML] An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer

J Jia, H Parikh, W Xiao, JW Hoskins, H Pflicke… - … medical genomics, 2013 - Springer
… investigated in pancreatic cancer [9–11] but genome wide … our understanding of the
pancreatic cancer genome, we … from normal and neoplastic pancreatic tissues by next generation …

A transcriptome-wide association study identifies candidate susceptibility genes for pancreatic cancer risk

D Liu, D Zhou, Y Sun, J Zhu, D Ghoneim, C Wu, Q Yao… - Cancer research, 2020 - AACR
… genes not yet reported for pancreatic cancer risk [6q27: … genome-wide association study.
Collectively, this analysis identified novel candidate susceptibility genes for pancreatic cancer

A transcriptome-wide association study identifies novel candidate susceptibility genes for pancreatic cancer

J Zhong, A Jermusyk, L Wu, JW Hoskins… - … the National Cancer …, 2020 - academic.oup.com
pancreatic cancer risk loci and possible causal genes, we performed a pancreatic cancer
transcriptome-… We integrated genome-wide association studies summary statistics from 9040 …

Transcriptome‐wide association study identifies multiple genes and pathways associated with pancreatic cancer

L Gong, D Zhang, Y Lei, Y Qian, X Tan… - Cancer Medicine, 2018 - Wiley Online Library
… A large-scale GWAS summary data of pancreatic cancer were used in this study.7 Briefly,
this GWAS comprised of 1896 individuals with pancreatic cancer and 1939 controls from 12 …

Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A

JW Hoskins, J Jia, M Flandez, H Parikh, W Xiao… - …, 2014 - academic.oup.com
… in pancreatic tumor-derived cells, we generated stable HNF1A-inducible clones in two
pancreatic cancer cell … In light of the established role of HNF1A in the regulation of pancreatic

[HTML][HTML] Development of a four-gene prognostic model for pancreatic cancer based on transcriptome dysregulation

J Yan, L Wu, C Jia, S Yu, Z Lu, Y Sun, J Chen - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
… In this study, a pancreatic cancer prognostic model based on transcriptome dysregulation
was developed, which was compatible across the microarray and RNA-Seq platforms and …

Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

M Chan-Seng-Yue, JC Kim, GW Wilson, K Ng… - Nature …, 2020 - nature.com
genomes and transcriptomes was generated from purified epithelium of primary and metastatic
tumors. Transcriptome … of the molecular subtypes of pancreatic cancer. We used these …

[HTML][HTML] Hypoxic microenvironment induced spatial transcriptome changes in pancreatic cancer

H Sun, D Zhang, C Huang, Y Guo, Z Yang… - Cancer Biology & …, 2021 - ncbi.nlm.nih.gov
… of pancreatic cancer cells 30,31 . Therefore, this study compared the transcriptomes of the
… effect of hypoxia on transcriptome heterogeneity of pancreatic cancer. The results indicated …

[HTML][HTML] … of pyroptosis-related genes in predicting prognosis and immunological characteristics of pancreatic cancer from the perspective of genome and transcriptome

J Zhang, X You, D Kang, G Zhou - Frontiers in Oncology, 2022 - frontiersin.org
… Current first-line therapies for advanced pancreatic cancer … specimens of pancreatic
cancer, the pancreatic cancer tumor … new targets for the treatment of pancreatic cancer (13). …

[PDF][PDF] Identification of miRNA-mRNA crosstalk in pancreatic cancer by integrating transcriptome analysis.

J Yang, Y Zeng - European Review for Medical & …, 2015 - europeanreview.org
… In this study, we combined mRNA and miRNA transcriptomes of pancreatic cancer with
miRNA target predictions to detect not only the expression dynamics of mRNA and miRNA, but …