[HTML][HTML] Metabolic reprogramming of immune cells in pancreatic cancer progression

H Xiang, R Yang, J Tu, Y Xi, S Yang, L Lv, X Zhai… - Biomedicine & …, 2023 - Elsevier
… the progress of pancreatic cancer, acrossing metabolic reprogramming and key metabolic
pathways … At present, the hotspots of metabolic reprogramming of immune cells in pancreatic

[HTML][HTML] Metabolic reprogramming due to hypoxia in pancreatic cancer: Implications for tumor formation, immunity, and more

X Hao, Y Ren, M Feng, Q Wang, Y Wang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
metabolic reprogramming, and its contribution to immunotherapy resistance in pancreatic
cancer. … Regarding the metabolic reprogramming of pancreatic cancer cells in hypoxia, several …

[HTML][HTML] Metabolic reprogramming of pancreatic cancer mediated by CDK4/6 inhibition elicits unique vulnerabilities

J Franco, U Balaji, E Freinkman, AK Witkiewicz… - Cell reports, 2016 - cell.com
Due to loss of p16ink4a in pancreatic ductal adenocarcinoma (PDA), pharmacological
suppression of CDK4/6 could represent a potent target for treatment. In PDA models, CDK4/6 …

Metabolic reprogramming and cancer progression

B Faubert, A Solmonson, RJ DeBerardinis - Science, 2020 - science.org
… In a mouse pancreatic cancer model, ablating oncogenic Kras from established tumors
revealed a fraction of cells that survive and eventually propagate. These dormant cells display …

Regulation of metabolic reprogramming by tumor suppressor genes in pancreatic cancer

M Liu, W Liu, Y Qin, X Xu, X Yu, Q Zhuo, S Ji - Experimental Hematology & …, 2020 - Springer
… tried to explain the mechanisms of abnormal cancer metabolism from the perspective of tumor
metabolic reprogramming was regulated by tumor suppressor genes in pancreatic cancer

The interactive role of inflammatory mediators and metabolic reprogramming in pancreatic cancer

Y Ohara, P Valenzuela, SP Hussain - Trends in cancer, 2022 - cell.com
… signaling promote protumorigenic events, including metabolic reprogramming with several
inter-… role of inflammatory signaling and metabolic reprogramming with emerging evidence of …

Metabolic alterations in pancreatic cancer progression

E Vernucci, J Abrego, V Gunda, SK Shukla… - Cancers, 2019 - mdpi.com
… Our results delineate the cellular metabolism reprogramming that starts early in PDAC
progression and demonstrate that such changes are consistently observed across different models…

Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis

OG McDonald, X Li, T Saunders, R Tryggvadottir… - Nature …, 2017 - nature.com
During the progression of pancreatic ductal adenocarcinoma (PDAC), heterogeneous subclonal
populations emerge that drive primary tumor growth, regional spread, distant metastasis…

The role of metabolic reprogramming in pancreatic cancer chemoresistance

C Liu, C Li, Y Liu - Frontiers in Pharmacology, 2023 - frontiersin.org
… involves glucose, lipid, and amino acid metabolism and … in metabolism during the progression
of pancreatic cancer and their … , and summarized current studies on metabolic inhibitors. …

Metabolic reprogramming by driver mutation-tumor microenvironment interplay in pancreatic cancer: new therapeutic targets

HB Andersen, R Ialchina, SF Pedersen… - Cancer and Metastasis …, 2021 - Springer
… In this review, we highlight key findings and potential future directions of pancreatic
cancer metabolism research, specifically focusing on novel therapeutic opportunities. …