Pancreatic Cancer Biomarkers: Oncogenic Mutations, Tissue and Liquid Biopsies, and Radiomics—A Review

MJ Amaral, RC Oliveira, P Donato… - Digestive diseases and …, 2023 - Springer
Pancreatic cancer is one of the most fatal malignancies, as … the most common pancreatic
cancer biomarkers with emphasis … Together with biomarkers in imaging, can represent valuable …

Biomarkers in pancreatic cancer: diagnostic, prognostic, and predictive

ZV Fong, JM Winter - The Cancer Journal, 2012 - journals.lww.com
… There has been a recent explosion in the pancreatic cancer biomarker field with more than
2000 biomarker studies implicating thousands of informative genes as candidate biomarkers. …

New biomarkers and targets in pancreatic cancer and their application to treatment

E Costello, W Greenhalf, JP Neoptolemos - … reviews Gastroenterology & …, 2012 - nature.com
… tumours contain mutations in the KRAS2 oncogene (KRAS1 is a pseudogene and KRAS2
is the proto-oncogene that is commonly mutated in certain cancer types), resulting in a …

MicroRNAs in pancreatic cancer: biomarkers, prognostic, and therapeutic modulators

AZ Daoud, EJ Mulholland, G Cole, HO McCarthy - BMC cancer, 2019 - Springer
… therapeutic options renders pancreatic cancer as a major … mechanisms involved in
pancreatic cancer progression. … Oncogene addiction materialises when a cancer requires the …

MicroRNA functional network in pancreatic cancer: from biology to biomarkers of disease

J Wang, S Sen - Journal of biosciences, 2011 - Springer
… In this \article, we review the existing literature in the field documenting the significance of
aberrantly expressed miRs in human pancreatic cancer and discuss how the oncogenic miRs …

An integrative data mining and omics-based translational model for the identification and validation of oncogenic biomarkers of pancreatic cancer

NP Long, KH Jung, NH Anh, HH Yan, TD Nghi, S Park… - Cancers, 2019 - mdpi.com
… Dataset GSE28735 contained 45 matching pairs of pancreatic cancer and adjacent non-…
upregulated genes in an effort to identify oncogenic biomarkers for the diagnosis, prognosis, …

Biomarkers for pancreatic cancer: promising new markers and options beyond CA 19-9

UK Ballehaninna, RS Chamberlain - Tumor Biology, 2013 - Springer
biomarkers, the role of microRNAs, and pancreatic cancer … a preferred tumor marker for
pancreatic adenocarcinoma. This … The other oncogenes affected by pancreatic cancer involve …

Biomarkers and targeted therapy in pancreatic cancer

F Karandish, S Mallik - Biomarkers in cancer, 2016 - journals.sagepub.com
… cell surface biomarkers … in pancreatic cancer cells and PCSCs. Notch acts as the tumor
suppressor in the skin and small cell carcinomas but as an oncogenic protein in pancreatic cancer

Advances in biomarker research for pancreatic cancer

K Bhat, F Wang, Q Ma, Q Li, S Mallik… - Current …, 2012 - ingentaconnect.com
biomarkers with high specificity to PC are needed to reduce the mortality rate of pancreatic
canceroncogenic phenotypes in pancreatic cancer cells and is increasingly expressed during …

Combining clinicopathological predictors and molecular biomarkers in the oncogenic K-RAS/Ki67/HIF-1α pathway to predict survival in resectable pancreatic cancer

R Qin, TC Smyrk, NR Reed, RL Schmidt… - … journal of cancer, 2015 - nature.com
pancreatic cancer. Here, we report that SIAH is a tumour-specific biomarker in pancreatic
cancer … (Figure 2); and individually, the selected five biomarkers, EGFR, phospho-ERK, SIAH, …