… with the pathologic grade of pancreatic cancer [13]. Ng and colleagues showed that PI3K
pathway is constitutively activated in pancreatic cancer cells and PI3K suppression increases …

… indicated that scoparone inhibits pancreatic cancer cell proliferation, migration, and
invasion, and induced cell cycle arrest and apoptosis through the PI3K/Akt signaling pathway. …

… Thus, in PTEN siRNA transfected pancreatic cancer cells, the PI3K–Akt signaling pathway
was activated, subsequently enhancing VEGF expression and increasing eNOS activation. …

… To elucidate whether inhibiting the PI3K/Akt signaling pathway … Inhibition of the PI3K/Akt
signaling pathway significantly … invasion via the PI3K/Akt signaling pathway. LAMB3 knockdown …

… pancreatic cancer patients. In this review, we focus on PI3K/AKT/mTOR inhibitors that have
shown great anti-tumor potential in studies performed on xenograft models and pancreatic …

… the PI3K-Akt signaling pathway and promotes pancreatic cancer growth in vivo To determine
whether IGF2BP2 promotes pancreatic cancer cell growth via the PI3K-Akt pathway in vivo …

… PI3K/AKT/mTOR signaling pathway, a main downstream effector of KRAS is involved in the
… PI3K/AKT/mTOR pathway could provide valuable assets for treatment of pancreatic cancer …

… signalling pathway and in particular Class I PI3K isoforms for pancreatic cancer treatment.
Isoform-specificity of PI3K inhibitors are currently designed to achieve the same goal as pan-…

… disclosed that activation of TGFβ1 and PI3K/AKT signal might be responsible for TMEM158‐…
TGFβ1 and PI3K/AKT signaling pathways, highlighting its potential as a tumor promoter and …

… dependent, and down-regulated phosphorylation of AKT by LY294002 or mk2206 could …
role of PI3K/AKT signaling pathway on the radioresistance of pancreatic cancer cells induced by …