… Purpose: Pancreatic cancer is characterized by intratumoral hypoxia, … in pancreatic cancer
has not been tested. Experimental Design: We orthotopically transplanted pancreatic cancer …

… Since pancreatic ductal carcinoma is unusually … of pancreatic cancer, surgical resection
remains to be the only potentially curative therapy. The potential discoveries of pancreatic cancer …

… for developing improved therapies for this aggressive cancer. Although they are the … pancreatic
cancer and effective therapies for this disease remain elusive (2, 6–8). Pancreatic cancer …

… to anti-cancer treatments that … killing the “BAD” aim to normalize the tumor microenvironment
and are recommended to enhance anti-cancer immune-system efficacy in pancreatic cancer…

… Pancreatic cancer (PC) is an aggressive cancer and a leading cause of cancer death [1].
Most of the patients diagnosed with PC will die of their disease within 5 years [2]. Despite …

… The current 5-year survival rate for patients with primary pancreas cancer is only 7.5% as
compared to 1% in the 1950s, representing both the worst prognosis and lowest absolute …

… Pancreatic cancer is the fourth leading cause of cancer-… Conventional treatments for pancreatic
cancer are scarcely … Suicide or prodrug-converting cancer gene therapy may represent a …

… In light of these results, we propose AdΔΔ as a potent new therapeutic for pancreatic cancers,
specifically in combination with DNA-damaging drugs. In addition, the wider spectrum of …

… cancer immunotherapy and the potential of this field to deliver effective treatment options for
pancreatic cancer … meaningful clinical responses in pancreatic cancer patients. Results from …

… ACK is an inventor on patents pertaining to KRAS regulated metabolic pathways, redox
control pathways in pancreatic cancer, targeting GOT1 as a therapeutic approach, and the …