[HTML][HTML] lncRNA GAS5 reverses EMT and tumor stem cell-mediated gemcitabine resistance and metastasis by targeting miR-221/SOCS3 in pancreatic cancer

B Liu, S Wu, J Ma, S Yan, Z Xiao, L Wan… - … Therapy-Nucleic Acids, 2018 - cell.com
… of GAS5 was downregulated in PC tissue compared with adjacent normal pancreatic … Our
study thus found that GAS5 overexpression inhibited xenograft tumor growth, metastasis, and …

[HTML][HTML] Long non-coding RNA GAS5 suppresses pancreatic cancer metastasis through modulating miR-32-5p/PTEN axis

ZQ Gao, J Wang, DH Chen, XS Ma, Y Wu, Z Tang… - Cell & bioscience, 2017 - Springer
… of lncRNA GAS5 in PC cell metastasis. The main new achievement of this study includes:
(1) LncRNA GAS5 … the existence of GAS5/miR-32-5p/PTEN signaling pathway in pancreatic

Downregulation of gas5 increases pancreatic cancer cell proliferation by regulating CDK6

X Lu, Y Fang, Z Wang, J Xie, Q Zhan, X Deng… - Cell and tissue …, 2013 - Springer
… biology and that lncRNA gas5 (growth arrest-specific 5) regulates breast … level of gas5 in
pancreatic cancer tissues and define the role of gas5 in the regulation of pancreatic cancer cell …

LncRNA GAS5 Regulates Gemcitabine Resistance in Pancreatic Carcinoma by Targeting miRNA-21

K Huang, G Yang - Annals of Clinical & Laboratory Science, 2023 - Assoc Clin Scientists
carcinoma cells. We first detected the lncRNA GAS5 expression in pancreatic carcinoma
We found a significant decrease in GAS5 level in PAN-1/GEM and PaCa-2/GEM cells as …

[HTML][HTML] Long non-coding RNA GAS5 antagonizes the chemoresistance of pancreatic cancer cells through down-regulation of miR-181c-5p

ZQ Gao, J Wang, DH Chen, XS Ma, W Yang… - Biomedicine & …, 2018 - Elsevier
… of GAS5 inhibited tumor growth in pancreatic cancer-bearing mice model. … pancreatic cancer.
This study revealed the promising prognostic or targeted role of GAS5 in pancreatic cancer. …

[HTML][HTML] Long noncoding RNA GAS5 in human cancer

X Yang, Z Xie, X Lei, R Gan - Oncology letters, 2020 - spandidos-publications.com
GAS5), a well‑known lncRNA that acts as a tumor suppressor but is suppressed in multiple
types of cancer, including mammary carcinoma, prostate cancer… -cancerous pancreatic ductal …

Altered expression of long non-coding RNA GAS5 in digestive tumors

S Lu, Z Su, W Fu, Z Cui, X Jiang, S Tai - Bioscience Reports, 2019 - portlandpress.com
GAS5 in pancreatic cancer Pancreatic cancer is one of the malignant tumors of the
digestive tract. It has a high degree of malignancy and is difficult to diagnose and treat. The 5-year …

[HTML][HTML] LncRNA GAS5 inhibits Invasion and Migration of Lung Cancer through influencing EMT process

L Zhu, D Zhou, T Guo, W Chen, Y Ding, W Li… - … of Cancer, 2021 - ncbi.nlm.nih.gov
… various cancers, including pancreatic cancer 15 , lung cancer 16 and bladder cancer 17 . In
GAS5 and lung cancer cells. Meanwhile, the potential role of GAS5 as an anti-cancer agent …

The role of long non-coding RNA GAS5 in cancers

J Ji, X Dai, SCJ Yeung, X He - Cancer management and research, 2019 - Taylor & Francis
… that GAS5 expression was lower in pancreatic cancer than … of GAS5 can inhibit cell
proliferation in pancreatic cancer by … of GAS5 was associated with chemoresistance in pancreatic

Downregulation of long noncoding RNA Gas5 affects cell cycle and insulin secretion in mouse pancreatic β cells

F Jin, N Wang, Y Zhu, L You, L Wang, W De… - Cellular Physiology and …, 2018 - karger.com
lncRNA Gas5 may play a role in regulating pancreatic β cell function. In addition, this study
identified lncRNA Gas5 as a novel regulator of insulin synthesis and secretion in pancreatic β …