[HTML][HTML] Metabolism remodeling in pancreatic ductal adenocarcinoma
… metabolism remodeling to facilitate PDAC development. In this review, we focus on the
dysregulation of metabolism … on the effect of metabolic remodeling of the tumor microenvironment …
dysregulation of metabolism … on the effect of metabolic remodeling of the tumor microenvironment …
Metabolic rewiring of pancreatic ductal adenocarcinoma: New routes to follow within the maze
O Olivares, S Vasseur - International journal of cancer, 2016 - Wiley Online Library
… metabolic rewiring goes far further than previously thought but studying the influence of
metabolic remodeling … Detecting oncometabolites or other metabolic markers have been of …
metabolic remodeling … Detecting oncometabolites or other metabolic markers have been of …
Metabolic plasticity in heterogeneous pancreatic ductal adenocarcinoma
C Liang, Y Qin, B Zhang, S Ji, S Shi, W Xu, J Liu… - … et Biophysica Acta (BBA …, 2016 - Elsevier
… However, accumulating evidence has revealed that plasticity is another feature of PDA
metabolism, in which each cancer cell could remodel the biochemical pathways of energy …
metabolism, in which each cancer cell could remodel the biochemical pathways of energy …
[HTML][HTML] Targets (metabolic mediators) of therapeutic importance in pancreatic ductal adenocarcinoma
V Rai, S Agrawal - International Journal of Molecular Sciences, 2020 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), an extremely aggressive invasive cancer, is the …
potential of metabolic mediators in PDAC along with stemness due to metabolic alterations …
potential of metabolic mediators in PDAC along with stemness due to metabolic alterations …
[HTML][HTML] … and chemoresistance in pancreatic ductal adenocarcinoma: Insights into targeting physicochemical barriers and metabolism as therapeutic approaches
TMA Carvalho, D Di Molfetta, MR Greco, T Koltai… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor
prognosis. The lack of early diagnosis and the absence of suitable biomarkers coupled with …
prognosis. The lack of early diagnosis and the absence of suitable biomarkers coupled with …
[HTML][HTML] The critical roles of activated stellate cells-mediated paracrine signaling, metabolism and onco-immunology in pancreatic ductal adenocarcinoma
Y Fu, S Liu, S Zeng, H Shen - Molecular cancer, 2018 - Springer
… In turn, it’s increasingly apparent that aPSCs regulate TME remodeling and promote … of
qPSCs to their activated state, which then results in stromal remodeling of PDAC [57, 58]. Further …
qPSCs to their activated state, which then results in stromal remodeling of PDAC [57, 58]. Further …
[HTML][HTML] Tumor microenvironment and metabolic remodeling in gemcitabine‐based chemoresistance of pancreatic cancer
Z Gu, Y Du, X Zhao, C Wang - Cancer Letters, 2021 - Elsevier
… Pancreatic ductal adenocarcinoma (PDAC) is a solid … Metabolic remodeling reduces GEM
transport and synthesis … ), immune cells, and metabolic remodeling in the induction of GEM …
transport and synthesis … ), immune cells, and metabolic remodeling in the induction of GEM …
[HTML][HTML] Metabolic pathways as a novel landscape in pancreatic ductal adenocarcinoma
A Ali, U Chianese, C Papulino, A Toraldo, MEA Abakar… - Cancers, 2022 - mdpi.com
… is dependent on metabolic conditions, … , and pancreatic ductal adenocarcinoma is no
exception. In this review, we describe the metabolic features of pancreatic ductal adenocarcinoma …
exception. In this review, we describe the metabolic features of pancreatic ductal adenocarcinoma …
[HTML][HTML] Targeting cancer cell metabolism in pancreatic adenocarcinoma
R Cohen, C Neuzillet, A Tijeras-Raballand, S Faivre… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… Pancreatic ductal adenocarcinoma (PDAC) is expected to become the second leading …
acid contributes to pro-tumor immunologic remodeling by promoting chronic inflammation, while …
acid contributes to pro-tumor immunologic remodeling by promoting chronic inflammation, while …
[HTML][HTML] Divergent roles of mitochondria dynamics in pancreatic ductal adenocarcinoma
CA Carmona-Carmona, E Dalla Pozza, G Ambrosini… - Cancers, 2022 - mdpi.com
… Pancreatic ductal adenocarcinoma is one of the most lethal … The study of metabolic alterations
of PDAC is of crucial … that regulate energy metabolism, and they remodel their structure by …
of PDAC is of crucial … that regulate energy metabolism, and they remodel their structure by …
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