SNP discovery using a pangenome: has the single reference approach become obsolete?

B Hurgobin, D Edwards - Biology, 2017 - mdpi.com
… The advent of next-generation sequencing (NGS) coupled with the heritability of SNPs make
them ideal markers for genetic analysis of human, animal, and microbial data. SNPs have …

A Reference Pan-Genome Approach to Comparative Bacterial Genomics: Identification of Novel Epidemiological Markers in Pathogenic Campylobacter

G Méric, K Yahara, L Mageiros, B Pascoe… - PloS one, 2014 - journals.plos.org
… However, 263 accessory genes, identified using the reference pan-genome approach in
this study, are absent in C. jejuni 11168 but present in the ST-45 complex. Amongst this …

[HTML][HTML] A pangenome approach for discerning species-unique gene markers for identifications of Streptococcus pneumoniae and Streptococcus pseudopneumoniae

L Gonzales-Siles, R Karlsson, P Schmidt… - Frontiers in cellular …, 2020 - frontiersin.org
… identify unique genomic markers, using pangenome analyses, … gene markers for S.
pneumoniae and S. pseudopneumoniae. The species-dependent presence of these unique markers

[HTML][HTML] Pan-genome analyses of the species Salmonella enterica, and identification of genomic markers predictive for species, subspecies, and serovar

CR Laing, MD Whiteside, VPJ Gannon - Frontiers in microbiology, 2017 - frontiersin.org
… the pan-genome among a group of sequences, and the SuperPhy platform, which utilizes this
pan-genome … In this study, we examined the pan-genome of 4893 genomes of Salmonella …

GWAS for genetics of complex quantitative traits: Genome to pangenome and SNPs to SVs and k‐mers

PK Gupta - BioEssays, 2021 - Wiley Online Library
… use of pangenomes and novel markers including structural … Pangenomes and SVs are now
available in humans, livestock, … of pangenomes using the above three approaches started …

Plant pangenomics: approaches, applications and advancements

MF Danilevicz, CGT Fernandez, JI Marsh… - Current opinion in plant …, 2020 - Elsevier
approaches for pangenome assembly, analysis and visualisation. In addition, we consider
the potential of pangenomes … molecular genetic markers such as SNPs, and the application of …

[HTML][HTML] … phylo-pangenomics reveals generalist lifestyles in representative Acinetobacter species and proposes candidate gene markers for species identification

OGG de Almeida, JPR Furlan, EG Stehling… - Gene, 2021 - Elsevier
… these strains through pangenomics analysis and also proposed new gene markers which
may … Both approaches conciliated an open pangenome structure for the genus Acinetobacter. …

panX: pan-genome analysis and exploration

W Ding, F Baumdicker, RA Neher - Nucleic acids research, 2018 - academic.oup.com
gene clusters in the pan-genome. This pipeline is coupled to a powerful yet easy-to-use
web-based visualization for interactive exploration of the pan-genome. The … A common approach

Design of a diagnostic system based on molecular markers derived from the ascomycetes pan-genome analysis: The case of Fusarium dieback disease

M Vázquez-Rosas-Landa, D Sánchez-Rangel… - Plos one, 2021 - journals.plos.org
… a pan-genome analysis … Pan-genome analysis revealed that 2,631 orthologue genes are
only shared by Fusarium spp., and on average 3,941 (SD ± 1,418.6) are species-specific genes

Challenges in gene-oriented approaches for pangenome content discovery

V Bonnici, E Maresi, R Giugno - Briefings in Bioinformatics, 2021 - academic.oup.com
gene-oriented approaches for characterizing pangenomes and compare them on the ability
to correctly identify gene … We use the term gene-oriented since we focus on approaches that …