Prognostic utility of BRAF mutation in papillary thyroid cancer

M Xing - Molecular and cellular endocrinology, 2010 - Elsevier
… The vast majority of thyroid cancers originate from follicular epithelial cells, which are … as
papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and anaplastic thyroid cancer (…

BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications

M Xing - Endocrine reviews, 2007 - academic.oup.com
… of thyroid cancer are papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and
anaplastic thyroid cancer (… The vast majority of thyroid cancers are PTC, which accounts for more …

BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer

M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
… shown that this BRAF mutation occurs in papillary thyroid cancer (PTC) … BRAF mutation
occurs exclusively in PTC and PTC-derived anaplastic thyroid cancers but not in normal thyroid

BRAF mutation in papillary thyroid carcinoma

Y Cohen, M Xing, E Mambo, Z Guo… - … the National Cancer …, 2003 - academic.oup.com
… (5%–20%) in papillary thyroid tumors (5). Our observation of a high frequency of BRAF-activating
mutations in papillary thyroid carcinoma suggests that BRAF activation and, in turn, …

The prevalence and prognostic value of BRAF mutation in thyroid cancer

E Kebebew, J Weng, J Bauer, G Ranvier… - Annals of …, 2007 - journals.lww.com
… They have shown that 51% of pure papillary thyroid cancers were BRAF positive, which is
similar to the 38% we have reported in our own patient population with papillary thyroid cancer

BRAF mutation in papillary thyroid cancer and its value in tailoring initial treatment: a systematic review and meta-analysis

RP Tufano, GV Teixeira, J Bishop, KA Carson, M Xing - Medicine, 2012 - journals.lww.com
… of disease recurrence or persistence and progression. The B-type Raf kinase (BRAF V600E)
mutation in exon 15 of the BRAF … of thyroid cancer, papillary thyroid cancer (PTC)—a tumor

BRAFV600E Mutation is Associated with Tumor Aggressiveness in Papillary Thyroid Cancer

S Kim, KE Lee, JP Myong, J Park, YK Jeon… - World journal of …, 2012 - Springer
BRAF V600E mutation is the most common genetic alteration found in papillary thyroid cancer
(… the prevalence of the BRAF V600E mutation in tumor samples and its association with …

Clinical Implication of Hot Spot BRAF Mutation, V599E, in Papillary Thyroid Cancers

H Namba, M Nakashima, T Hayashi… - The Journal of …, 2003 - academic.oup.com
cancers. The aim of the present study was to determine the frequency of BRAF mutations in
thyroid cancer … We analyzed exons 11 and 15 of BRAF gene in six human thyroid cancer cell …

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
BRAF V600E–negative and BRAF V600E–positive groups for all patients and for patients
with conventional papillary thyroid cancer (PTC). Follow-up time is truncated at 12 years. …

[PDF][PDF] BRAF (V600E) mutation and the biology of papillary thyroid cancer

F Frasca, C Nucera, G Pellegriti, P Gangemi… - … -related cancer, 2008 - academia.edu
papillary thyroid carcinoma display mostly identical BRAF status. International Journal of
Cancer … & Glattre E 1993 Incidence pattern of thyroid cancer in Norway: influence of birth cohort …