… -specific PCR and in 10 thyroid tumor cell lines by DNA … BRAF was mutated in 8 of 10
thyroid tumor cell lines, including 2 of 2 papillary carcinoma cell lines, 4 of 5 anaplastic carcinoma …

… BRAF mutation represents the most common oncogenic event in sporadic papillary thyroid
cancer (PTC). There are, however, significant discrepancies regarding the overall frequency …

… to investigate the frequency of the BRAF mutation in papillary thyroid carcinoma (PTC) of …
conventional papillary carcinomas in the thyroid gland were evaluated. The BRAF missense …

… BRAF mutations were of classic papillary histotype. We found no mutations in exon 11 of
BRAF in any of the 128 thyroid tumor … lung cancer cell line as a positive control (BRAF G468A ; …

… to investigate the frequency of BRAF mutations in human papillary thyroid carcinoma (PTC) …
of the BRAF mutation with the clinicopathological features of both of these thyroid disorders. …

… BRAF mutations are closely associated with aggressive … papillary thyroid cancer. Accordingly,
aggressive treatment should be considered for papillary thyroid cancer patients with BRAF …

… histology remained independently predictive of the BRAF mutation on … for BRAF mutations
13-16, 19. The significant association between the BRAF mutation and the classic papillary …

… In this meta-analysis, the association of the BRAF V600E mutation with cancer-specific
mortality was not evaluated. To date, Elisei et al reported increased mortality in those with the …

… BRAF mutation is the most common genetic alternation … thyroid cancer, particularly in papillary
thyroid cancer (PTC). Excessive activation of BRAF/MAPK signaling pathway due to BRAF …

… not been previously used for BRAF mutation studies in thyroid cancer, with this approach, …
of the effect of BRAF knockdown on the behaviors of PTC cells that harbor BRAF mutation. In …