BRAF mutation in papillary thyroid cancer and its value in tailoring initial treatment: a systematic review and meta-analysis

RP Tufano, GV Teixeira, J Bishop, KA Carson, M Xing - Medicine, 2012 - journals.lww.com
… The B-type Raf kinase (BRAF V600E) mutation in exon 15 of the BRAF gene has been … the
most prevalent form of thyroid cancer, papillary thyroid cancer (PTC)—a tumor type with high …

BRAFV600E mutation is associated with an increased risk of nodal recurrence requiring reoperative surgery in patients with papillary thyroid cancer

CJ O'Neill, M Bullock, A Chou, SB Sidhu, LW Delbridge… - Surgery, 2010 - Elsevier
… the BRAF V600E mutation on long-term disease outcomes within an Australian cohort of
patients. The data suggest that patients with tumors containing BRAF V600E … with BRAF V600E -…

Diagnostic value of fine needle aspiration BRAFV600E mutation analysis in papillary thyroid cancer: a systematic review and meta-analysis

N Fnais, C Soobiah, ALQ Khalid, JS Hamid, L Perrier… - Human pathology, 2015 - Elsevier
… , univariate pooled sensitivity using FNA and BRAF V600E results was 52% (95% … BRAF
V600E mutation analysis has a low sensitivity in diagnosing papillary thyroid cancer in thyroid

Study of peripheral BRAFV600E mutation as a possible novel marker for papillary thyroid carcinomas

JY Kwak, JJ Jeong, SW Kang, S Park, JR Choi… - Head & …, 2013 - Wiley Online Library
papillary thyroid cancer positive for the BRAF V600EBRAF V600E mutation can be
detected in serum, an efficient diagnostic algorithm may be developed to diagnose thyroid cancer

[HTML][HTML] BRAFV600E mutation in papillary thyroid microcarcinoma: a genotype–phenotype correlation

RK Virk, AL Van Dyke, A Finkelstein, A Prasad… - Modern pathology, 2013 - Elsevier
… we demonstrated that papillary thyroid carcinoma with BRAF V600E mutation was … the
incidence of BRAF V600E mutation in papillary microcarcinoma, and ask if the mutated tumors are …

Meta-Analyses of Association Between BRAFV600E Mutation and Clinicopathological Features of Papillary Thyroid Carcinoma

Q Zhang, S Liu, Q Zhang, Y Guan, Q Chen… - Cellular Physiology and …, 2016 - karger.com
… and 9,951 (39.4%) were tested negative for BRAF mutation. Negative status of BRAFV600E
mutation … By contrast, positive status of BRAFV600E mutation was a significant predictor of …

The BRAF mutation is useful for prediction of clinical recurrence in low‐risk patients with conventional papillary thyroid carcinoma

TY Kim, WB Kim, YS Rhee, JY Song… - Clinical …, 2006 - Wiley Online Library
… further test the hypothesis that the BRAF V600E mutation is a prognostic indicator for PTC.
The study determined the prevalence of the BRAF V600E mutation in conventional PTC tissue …

The prevalence and prognostic value of BRAF mutation in thyroid cancer

E Kebebew, J Weng, J Bauer, G Ranvier… - Annals of …, 2007 - journals.lww.com
… In patients with conventional papillary thyroid cancer, BRAF V600E mutation was associated
with older age (P = 0.0381), lymph node metastasis (P = 0.0323), distant metastasis (P = …

Both BRAF V600E Mutation and Older Age (≥65 Years) are Associated with Recurrent Papillary Thyroid Cancer

GM Howell, SE Carty, MJ Armstrong… - Annals of surgical …, 2011 - Springer
Purpose This study was designed to examine the aggressive features of BRAF-positive
papillary thyroid cancer (PTC) and association with age. Methods We compared the …

BRAF V600E mutation and expression of proangiogenic molecular markers in papillary thyroid carcinomas

C Durante, G Tallini, E Puxeddu… - European journal of …, 2011 - academic.oup.com
… from Dr C Nucera (Harvard Medical School, Boston, MA, USA), whose team established
this cell line from undifferentiated human thyroid carcinoma cells expressing the BRAF V600E